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  1. Content type: Research

    Most individuals who learn about hereditary cancer manage well, but identification of subgroups who find this knowledge burdening would allow psychosocial intervention. The objective of the study was to assess...

    Authors: Helle Vendel Petersen, Steen Ladelund, Christina Carlsson and Mef Nilbert

    Citation: Hereditary Cancer in Clinical Practice 2013 11:7

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  2. Content type: Research

    Follow-up studies of psoriasis patients indicate an increased risk in the occurrence of malignancies at different sites of origin. Population stratification and/or complicated interpretation of evidence on the...

    Authors: Romuald Maleszka, Katarzyna Paszkowska-Szczur, Ewa Soczawa, Magdalena Boer, Monika Różewicka-Czabańska, Joanna Wiśniewska, Aneta Mirecka, Lidia Krysztoforska, Zygmunt Adamski, Jan Lubinski and Tadeusz Dębniak

    Citation: Hereditary Cancer in Clinical Practice 2013 11:6

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  3. Content type: Letter to the Editor

    PIK3CA is the most frequently mutated oncogene in human cancers. PIK3CA is phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha. It controls cell growth, proliferation, motility, survival, d...

    Authors: Sidra German, Hafiz Muhammad Aslam, Shafaq Saleem, Aisha Raees, Tooba Anum, Arsalan Ahmad Alvi and Abdul Haseeb

    Citation: Hereditary Cancer in Clinical Practice 2013 11:5

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  4. Content type: Review

    Hamartomas are tumour-like malformations, consisting of disorganized normal tissues, typical of the site of tumour manifestation. Familial manifestation of hamartomatous polyps can be noted in juvenile polypos...

    Authors: Zoran Stojcev, Pawel Borun, Jacek Hermann, Piotr Krokowicz, Wojciech Cichy, Lukasz Kubaszewski, Tomasz Banasiewicz and Andrzej Plawski

    Citation: Hereditary Cancer in Clinical Practice 2013 11:4

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  5. Content type: Research

    Cancer is a shared family experience that might provide an opportunity for lifestyle change among at-risk family members. The purpose of this study was to assess receptivity and preferences for cancer risk red...

    Authors: Lisa A Howell, Pamela S Sinicrope, Tabetha A Brockman, Christi A Patten, Paul A Decker, Shawna L Ehlers, Ashley Nadeau, Kari G Rabe, Carmen Radecki Breitkopf and Gloria M Petersen

    Citation: Hereditary Cancer in Clinical Practice 2013 11:3

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  6. Content type: Review

    The history of specific therapy for hereditary tumors dates back to mid 1980s and involves a number of reports demonstrating regression of familial colon polyps upon administration of sulindac. Virtually no cl...

    Authors: Evgeny N Imyanitov and Tomasz Byrski

    Citation: Hereditary Cancer in Clinical Practice 2013 11:2

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  7. Content type: Case report

    Family history is among the few established risk factors for testicular germ cell tumor (TGCT). Approximately 1.4% of newly diagnosed TGCT patients report a positive family history of TGCT. Sons and siblings o...

    Authors: Rodrigo Santa Cruz Guindalini, Edite Paulo de Oliveira, Marina Cavalcanto Moroja Silvino, Paulo Marcelo Hoff and Bernardo Garicochea

    Citation: Hereditary Cancer in Clinical Practice 2013 11:1

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  8. Content type: Review

    Worldwide, gastric cancer is one of the most common forms of cancer, with a high morbidity and mortality. Several environmental factors predispose to the development of gastric cancer, such as Helicobacter pylori

    Authors: Ingrid P Vogelaar, Rachel S van der Post, Tanya M Bisseling, J Han JM van Krieken, Marjolijn JL Ligtenberg and Nicoline Hoogerbrugge

    Citation: Hereditary Cancer in Clinical Practice 2012 10:18

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  9. Content type: Meeting abstract

    Authors: Andrzej Plawski, Paweł Boruń, Tomasz Banasiewicz, Jacek Paszkowski, Agnieszka Stembalska, Maria Sąsiadek, Monika Siołek, Beata Kozak - Klonowska, Izabela Brozek, Janusz Limon, Dorota Nowakowska, Grzegorz Kurzawski, Tomasz Byrski, Tomasz Gach, Diana Hodorowicz-Zaniewska, Anna Bartkowiak…

    Citation: Hereditary Cancer in Clinical Practice 2012 10(Suppl 4):A24

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    This article is part of a Supplement: Volume 10 Supplement 4

  10. Content type: Meeting abstract

    Authors: Grzegorz Sukiennicki, Magdalena Muszyńska, Tomasz Huzarski, Jacek Gronwald, Cezary Cybulski, Tadeusz Dębniak, Aleksandra Tołoczko-Grabarek, Oleg Oszurek, Anna Jakubowska, Antoni Morawski and Jan Lubiński

    Citation: Hereditary Cancer in Clinical Practice 2012 10(Suppl 4):A5

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    This article is part of a Supplement: Volume 10 Supplement 4

  11. Content type: Meeting abstract

    Authors: Katarzyna Kaczmarek, Anna Jakubowska, Grzegorz Sukiennicki, Magdalena Muszyńska, Katarzyna Jaworska-Bieniek, Katarzyna Durda, Tomasz Huzarski, Pablo Serrano-Fernandez, Tomasz Byrski, Jacek Gronwald, Satish Gupta and Jan Lubiński

    Citation: Hereditary Cancer in Clinical Practice 2012 10(Suppl 4):A6

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    This article is part of a Supplement: Volume 10 Supplement 4

  12. Content type: Meeting abstract

    Authors: Katarzyna Jaworska - Bieniek, Anna Jakubowska, Katarzyna Durda, Tomasz Huzarski, Pablo Serrano-Fernandez, Grzegorz Sukiennicki, Magdalena Muszyńska, Tomasz Byrski, Jacek Gronwald, Satish Gupta, Katarzyna Kaczmarek and Jan Lubiński

    Citation: Hereditary Cancer in Clinical Practice 2012 10(Suppl 4):A4

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    This article is part of a Supplement: Volume 10 Supplement 4

  13. Content type: Meeting abstract

    Authors: Katrzyna Jaworska-Bieniek, Satish Gupta, Katarzyna Durda, Magdalena Muszynska, Grzegorz Sukiennicki, Elżbieta Jaworowska, Tomasz Grodzki, Mieczysław Sulikowski, Piotr Woloszczyk, Janusz Wójcik, Jakub Lubiński, Cezary Cybulski, Tadeusz Dębniak, Marcin Lener, Steven A Narod, Ping Sun…

    Citation: Hereditary Cancer in Clinical Practice 2012 10(Suppl 4):A2

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    This article is part of a Supplement: Volume 10 Supplement 4

  14. Content type: Meeting abstract

    Authors: A Kurlapska, P Serrano-Fernández, T Starzyńska, E Małecka-Panas, G A Dąbrowski, T Dębniak, G Kurzawski, J Suchy, W Rogoza-Mateja, R J Scott and J Lubiński

    Citation: Hereditary Cancer in Clinical Practice 2012 10(Suppl 4):A26

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    This article is part of a Supplement: Volume 10 Supplement 4

  15. Content type: Meeting abstract

    Authors: T T Huzarski, B Górecka-Szyld, J J Huzarska, G Psut, G Wilk, R Sibilski, C Cybulski, B Kozak-Klonowska, M Siołek, E Kilar, D Czudowska, H Janiszewska, D Godlewski, A Mackiewicz, J Jarkiewicz-Tretyn, I Szabo-Moskal…

    Citation: Hereditary Cancer in Clinical Practice 2012 10(Suppl 4):A18

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    This article is part of a Supplement: Volume 10 Supplement 4

  16. Content type: Review

    During the past decade many new molecular methods for DNA and RNA analysis have emerged. The most popular thus far have been SSCP, HET, CMC, DGGE, RFLP or ASA, which have now been replaced by methods that are ...

    Authors: Grzegorz Kurzawski, Dagmara Dymerska, Pablo Serrano-Fernández, Joanna Trubicka, Bartłomiej Masojć, Anna Jakubowska and Rodney J Scott

    Citation: Hereditary Cancer in Clinical Practice 2012 10:17

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  17. Content type: Research

    Chemokine and chemokine receptors play an essential role in tumorigenesis. Although chemokine-associated single nucleotide polymorphisms (SNPs) are associated with various cancers, their impact on prostate can...

    Authors: LaCreis R Kidd, Dominique Z Jones, Erica N Rogers, Nayla C Kidd, Sydney Beache, James E Rudd, Camille Ragin, Maria Jackson, Norma McFarlane-Anderson, Marshall Tulloch-Reid, Seian Morrison, Guy N Brock, Shirish S Barve and Kevin S Kimbro

    Citation: Hereditary Cancer in Clinical Practice 2012 10:16

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  18. Content type: Case report

    Café au lait spots (CALS) are common dermatologic findings that can at the same time arise in a variety of pathologic conditions such as Neurofibromatosis type 1 (NF1), together with numerous hereditary syndro...

    Authors: Giovanni Ponti, Aldo Tomasi, Lorenza Pastorino, Cristel Ruini, Carmelo Guarneri, Victor Desmond Mandel, Stefania Seidenari and Giovanni Pellacani

    Citation: Hereditary Cancer in Clinical Practice 2012 10:15

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  19. Content type: Letter to the Editor

    The mutations of the RET proto-oncogene contributes to the development of MTC by increasing the activity of the receptor encoded by this gene. Variant T of polymorphism rs2435357 located in the enhancer of the...

    Authors: Pawel Borun, Sowinski Jerzy, Katarzyna Ziemnicka, Lukasz Kubaszewski, Daniel Lipinski and Andrzej Plawski

    Citation: Hereditary Cancer in Clinical Practice 2012 10:14

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  20. Content type: Case report

    Mutations in FLCN cause Birt-Hogg-Dubé syndrome, an autosomal dominant disorder notable for development of cutaneous fibrofolliculomas or trichodiscomas, a variety of renal tumors, and spontaneous pneumothorax du...

    Authors: Noralane M Lindor, Jan Kasperbauer, Jean E Lewis and Mark Pittelkow

    Citation: Hereditary Cancer in Clinical Practice 2012 10:13

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  21. Content type: Case report

    Paragangliomas are rare tumours with a prevalence of 1/10000 to 1/30000. Tumors arising from the paraganglia are characteristically of low malignant potential. Vertebral metastases are exceedingly rare, and on...

    Authors: Manuel Eduardo Ribeiro da Silva, Manuel João Queiroz de Fariados Santos Carvalho, António Pedro Cacho Rodrigues, Nuno Silva Morais Neves, António Moura Gonçalves, Rui Alexandre Peixoto Pinto and Davide Carvalho

    Citation: Hereditary Cancer in Clinical Practice 2012 10:12

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  22. Content type: Research

    Cyclin-dependent kinase 4 (CDK4) together with its regulatory subunit cyclin D1, governs cell cycle progression through G1 phase. Cyclin-dependent kinase inhibitors, including p16INK4A in turn regulate CDK4. In p...

    Authors: Maimoona Sabir, Ruqia Mehmood Baig, Ishrat Mahjabeen and Mahmood Akhtar Kayani

    Citation: Hereditary Cancer in Clinical Practice 2012 10:11

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  23. Content type: Research

    The molecular etiology of thyroid carcinoma (TC) and other thyroid diseases which may present malignant precursor lesions is not fully explored yet. The purpose of this study was to estimate frequency, type an...

    Authors: Hans-Juergen Schulten, Sherine Salama, Zuhoor Al-Mansouri, Reem Alotibi, Khalid Al-Ghamdi, Osman Abdel Al-Hamour, Hassan Sayadi, Hosam Al-Aradati, Adel Al-Johari, Etimad Huwait, Mamdooh Gari, Mohammed Hussain Al-Qahtani and Jaudah Al-Maghrabi

    Citation: Hereditary Cancer in Clinical Practice 2012 10:10

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  24. Content type: Review

    With the discovery that the hereditary cancer susceptibility disease Lynch syndrome (LS) is caused by deleterious germline mutations in the DNA mismatch repair (MMR) genes nearly 20 years ago, genetic testing ...

    Authors: Christopher D Heinen and LJ Rasmussen

    Citation: Hereditary Cancer in Clinical Practice 2012 10:9

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  25. Content type: Research

    Pancreatic cancer (PC) is considered the most lethal cancer and approximately 10% of PC is hereditary. The purpose of the study was to assess attitudes of at-risk family members with two or more relatives affe...

    Authors: Carmen Radecki Breitkopf, Pamela S Sinicrope, Kari G Rabe, Tabetha A Brockman, Christi A Patten, Robert R McWilliams, Shawna Ehlers and Gloria M Petersen

    Citation: Hereditary Cancer in Clinical Practice 2012 10:8

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  26. Content type: Research

    Breast cancer is the most prevalent malignancy in women in Western countries, currently accounting for one third of all female cancers. Familial aggregation is thought to account for 5–10 % of all BC cases, an...

    Authors: Nadine Jalkh, Jinane Nassar-Slaba, Eliane Chouery, Nabiha Salem, Nancy Uhrchammer, Lisa Golmard, Domique Stoppa-Lyonnet, Yves-Jean Bignon and André Mégarbané

    Citation: Hereditary Cancer in Clinical Practice 2012 10:7

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  27. Content type: Research

    A growing number of individuals are diagnosed with hereditary cancer. Though increased levels of anxiety and depression have been demonstrated around the time of genetic counselling, most individuals handle li...

    Authors: Katarina Bartuma, Mef Nilbert and Christina Carlsson

    Citation: Hereditary Cancer in Clinical Practice 2012 10:6

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