Department of Tumor Biology, Institute of Cancer Research, Oslo University Hospital, Oslo, Norway
Mev Dominguez-Valentin, Sigve Nakken, Eivind Hovig & Pål Møller
Department of Gastrointestinal Surgery, Helsinki University Central Hospital, Helsinki, Finland
Toni T. Seppälä, Laura Renkonen-Sinisalo & Anna Lepistö
Clinicum, University of Helsinki, Helsinki, Finland
Toni T. Seppälä
Division of Cancer and Genetics, Institute of Medical Genetics, Cardiff University School of Medicine, Cardiff, UK
Julian R. Sampson
The Royal Melbourne Hospital, Melbourne, Australia
Finlay Macrae, Ingrid Winship & John-Paul Plazzer
University of Melbourne, Melbourne, Australia
Finlay Macrae, Ingrid Winship & Douglas Tjandra
University of Manchester & Manchester University Hospitals Foundation Trust, Manchester, UK
D. Gareth Evans, Kate Green, Fiona Lalloo & James Hill
University of Newcastle and the Hunter Medical Research Institute, Callaghan, Australia
Rodney J. Scott
University of Newcastle, Newcastle upon Tyne, UK
John Burn
University Witten-Herdecke, Wuppertal, Germany
Gabriela Möslein
Department of Surgical Gastroenterology, Aalborg University Hospital, Aalborg, Denmark
Inge Bernstein
Central Finland Central Hospital, Education and Research, Jyväskylä, Finland
Kirsi Pylvänäinen
Research Programs Unit, Genome-Scale Biology, University of Helsinki, Helsinki, Finland
Laura Renkonen-Sinisalo & Anna Lepistö
Karolinska Institutet, Stockholm, Sweden
Annika Lindblom
St Mark’s Hospital, Department of Surgery and Cancer, Imperial College London, London, UK
Huw Thomas
University of Manchester and St Mary’s Hospital, Manchester, UK
Emma J. Crosbie
Hereditary Cancer Program, Catalan Institute of Oncology, Insititut d’Investigació Biomèdica de Bellvitge (IDIBELL), ONCOBELL Program, L’Hospitalet de Llobregat, Barcelona, Spain
Gabriel Capella, Marta Pineda, Matilde Navarro & Joan Brunet Vidal
Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain
Gabriel Capella, Marta Pineda, Matilde Navarro & Joan Brunet Vidal
Department of Clinical Genetics, Vejle Hospital, Vejle, Denmark
Karina Rønlund
Department of Surgery, Regional Hospital West Jutland, Egtved, Denmark
Randi Thyregaard Nielsen
Department of Oncology, Aalborg University Hospital, Aalborg, Denmark
Mette Yilmaz
Department of Pathology, Herlev Gentofte University Hospital, Herlev, Denmark
Louise Laurberg Elvang
High Risk and GI Cancer prevention Clinic, Gatro-Oncology Unit, The Department of Gastroenterology, Sheba Medical Center, Ramat Gan, Israel
Lior Katz
Leids Universitair Medisch Centrum, Leiden, Netherlands
Maartje Nielsen & Sanne W. ten Broeke
Center for Bioinformatics, Department of Informatics, University of Oslo, Oslo, Norway
Eivind Hovig
Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark
Lone Sunde
Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany
Matthias Kloor, Magnus v Knebel Doeberitz & Aysel Ahadova
Cooperation Unit Applied Tumor Biology, German Cancer Research Center (DKFZ), Heidelberg, Germany
Matthias Kloor, Magnus v Knebel Doeberitz & Aysel Ahadova
Department of Health Sciences Research, Mayo Clinic, Scottsdale, AZ, USA
Noralane Lindor
Medizinische Klinik und Poliklinik IV, Campus Innenstadt, Klinikum der Universität München, Munich, Germany
Verena Steinke-Lange & Elke Holinski-Feder
MGZ- Medical Genetics Center, Munich, Germany
Verena Steinke-Lange & Elke Holinski-Feder
Department of Surgery, Central Finland Central Hospital, Jyväskylä, Finland
Jukka-Pekka Mecklin
Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland
Jukka-Pekka Mecklin
MDV, TTS and PM designed the study, drafted the manuscript, collected the feedback and revised the manuscript accordingly. PM conducted the statistical analysis. PM and MD-V managed the PLSD data. All authors participated in PLSD data collection. All authors read, critically commented, and approved the final manuscript.