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  1. When BRCA1/2 genetic susceptibility testing was introduced in the clinic in the mid-nineties, the "Huntington protocol" was used in the counselling of individuals applying for genetic testing. This protocol inclu...

    Authors: Iris van Oostrom and Aad Tibben
    Citation: Hereditary Cancer in Clinical Practice 2004 2:19
    Content type: Review Published on:

  4. This paper highlights the need for carriers to be followed up by health professionals who understand the complexities of the BRCA syndrome. A BRCA carrier clinic has been established in London and regular follow ...

    Authors: Audrey Ardern-Jones and Rosalind Eeles
    Citation: Hereditary Cancer in Clinical Practice 2004 2:77
    Content type: Case report Published on:

  6. The aim of the study is to evaluate the incidence and phenotype - genotype characteristics of hereditary colorectal cancer syndromes in Latvia in order to develop the basis of clinical management for patients ...

    Authors: Arvids Irmejs, Andris Gardovskis, Viktors Borosenko, Marianna Bitina, Diana Aigare, Grzegorz Kurzawski, Janina Suchy, Bohdan Górski and Janis Gardovskis
    Citation: Hereditary Cancer in Clinical Practice 2003 1:49
    Content type: Research Published on:

  7. Denaturing high performance liquid chromatography is a relatively new method by which heteroduplex structures formed during the PCR amplification of heterozygote samples can be rapidly identified. The use of t...

    Authors: Cliff J. Meldrum, Mary McPhillips, Renee Crooks, Lesley Thomas, Ted Edkins, Rohanna Creegan, Ewan Miller, Michael Agrez and Rodney J. Scott
    Citation: Hereditary Cancer in Clinical Practice 2003 1:39
    Content type: Research Published on:

  8. The criteria for the diagnosis of HNPCC established by the ICG-HNPCC are very restrictive as they do not allow for the diagnosis of a large number of "suspected HNPCC" cases - these are families which do no fu...

    Authors: Józef Kładny, Gabriela Möslein, Torben Myrhøj, Grzegorz Kurzawski, Anna Jakubowska, Tadeusz Dębniak, Wojciech Petriczko, Michał Kozłowski, Tariq Al-Amawi, Marek Brzosko, Jacek Fliciński, Arkadiusz Jawień, Zbigniew Banaszkiewicz, Piotr Rychter and Jan Lubiński
    Citation: Hereditary Cancer in Clinical Practice 2003 1:34
    Content type: Research Published on:

  9. In addition to a relatively small number of well known hereditary cancer syndromes, hundreds of presumed or proven hereditary disorders have been observed to manifest cancer as a characteristic feature or as a...

    Authors: Rolf H. Sijmons and Gerard T.N. Burger
    Citation: Hereditary Cancer in Clinical Practice 2003 1:31
    Content type: Commentary Published on:

  11. HNPCC (Lynch syndrome) is the most common form of hereditary colorectal cancer (CRC), wherein it accounts for between 2-7 percent of the total CRC burden. When considering the large number of extracolonic canc...

    Authors: Henry T. Lynch, Jane F. Lynch, Trudy G. Shaw and Jan Lubiński
    Citation: Hereditary Cancer in Clinical Practice 2003 1:7
    Content type: Review Published on:
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Hereditary Cancer in Clinical Practice

ISSN: 1897-4287