Table 2 Description of patients with c.586 C > T (p.R196X) TP53 pathogenic variant
Case | Age at diagnosis of first tumor (years) | Age at death or age at end of follow-up (years) | Gender | Tumor description |
|---|---|---|---|---|
Present case (2023) Colombia | 12 | 38 (death) | Female | Femur osteosarcoma, ductal carcinoma of the breast, high-grade breast sarcoma, pleomorphic sarcoma of the left upper limb, infiltrating lobular carcinoma of the breast, gastric adenocarcinoma, leiomyosarcoma of the right upper limb, high-grade pleomorphic renal sarcoma |
Bendig, et al. [11] Germany | 1 | 1 (follow-up) | Male | Rhabdomyosarcoma |
Vahteristo, et al. [12] Finland | 32 | 37 (follow-up) | Female | Liposarcoma, breast cancer |
Villani, et al. [13] Canada | 35 | 39 (follow-up) | Female | Colonic adenoma, intraductal carcinoma of the breast |