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Table 1 Description of patient’s tumors

From: Li-Fraumeni syndrome presenting with de novo TP53 mutation, severe phenotype and advanced paternal age: a case report

Morphology

Topography

Age at diagnosis

Clinical staging

Treatment

Osteosarcoma

Right femur

12

*

Surgery (distal femur resection)

and chemotherapy

Ductal carcinoma in situ

Right breast

26

0 (pT2 pN0 MX)

Surgery (radical mastectomy)

High-grade stromal sarcoma

Right breast

26

0 (pT2 pN0 MX)

Surgery (radical mastectomy) and chemotherapy

High-grade pleomorphic sarcoma

Left upper limb

(epitrochlear)

27

0 (pT1 pN0 M0)

Surgery (excision)

Invasive lobular carcinoma

Left breast

28

0 (pT2 pN0 MX)

Surgery (radical mastectomy)

Diffuse gastric adenocarcinoma with bilateral Krukenberg tumors

Stomach (lesser curvature)

35

IV (pT2 pN0 M1)

Surgery (cytoreduction, radical gastrectomy, Sugarbaker procedure)

Leiomyosarcoma

Right upper limb (epitrochlear)

35

II (pT2, pN0, M0)

Surgery (excision) and radiotherapy

High-grade pleomorphic sarcoma

Left kidney

37

II (pT2b pN0 M0)

Surgery (radical nephrectomy)

  1. *No data