Table 3 Sensitivity of clinical criteria in different studies
From: Diagnosis of patients with Lynch syndrome lacking the Amsterdam II or Bethesda criteria
Country/authors | Patients with LS | Amsterdam I | Amsterdam II | Revised Bethesda criteria1 | Cancer type |
|---|---|---|---|---|---|
United States of America (USA), Finland [16] | 312 | 41 (13%) | 85 (27%) | 214 (69%) | Colorectal cancer |
Norway [13] | 514 | 49 (10%) | 79 (15%) | * | Colorectal cancer |
China [31] | 6 | * | 2 (33%) | 2 (33%) | Endometrial cancer |
Canada [32] | 13 | * | 2 (15%) | 9 (69%) | Endometrial cancer |
Australia [33] | 3 | 0 (0%) | 0 (0%) | 0 (0%) | Endometrial cancer |
USA [34] | 8 | * | 1 (13%) | 0 (0%) | Endometrial cancer |
USA [34] | 16 | * | 8 (50%) | 12 (75%) | Colorectal cancer |
Korea [35] | 30 | * | 20 (67%) | * | Endometrial cancer |
Spain [36] | 14 | * | 7 (50%) | 12 (86%) | Colorectal cancer |
USA [37] | 5 | * | 1 (20%) | 2 (40%) | Colorectal cancer |
Scotland [29] | 38 | * | 16 (42%) | 36 (95%) | Colorectal cancer |
Portugal [38] | 4 | * | 0 (0%) | 3 (75%) | Colorectal cancer |
China [39] | 93 | * | 9 (10%) | 76 (82%) | Colorectal cancer |