Table 4 Comparison of genetic counseling, genetic testing, and the incidence of Lynch syndrome-associated colorectal cancer before and after multistep approach with multidisciplinary team
P-MA group n = 26 | MA group n = 26 | P-value | |
|---|---|---|---|
Pre-genetic counseling, n (%) | NA | 16 (61.5) | |
Genetic counseling, n (%) | 2 (7.7) | 9 (34.6) | 0.04 |
Genetic test, n (%) | 1 (3.8) | 8 (30.8) | 0.02 |
Hereditary colorectal cancer, n (%) | 1 (3.8) | 5 (19.2) | 0.19 |
Lynch syndrome, n (%) | 1 (3.8) | 4 (15.3) | 0.32* |
MLH1 | 1 | 2 | |
PMS2 | 0 | 1 | |
MSH2 | 0 | 1 | |
Lynch-like syndrome | 0 | 1 | 1.00 |
The incidence of Lynch syndrome-associated colorectal cancer (%) | 0.3 | 2.5 | 0.03 |