Table 1 Clinical characteristics of the enrolled patients
P-MA group n = 323 | MA group n = 199 | P-value | |
|---|---|---|---|
Age at surgery, years, median (range) | 70 (39–95) | 71 (32–95) | 0.74 |
Male/female, n | 190/133 | 114/85 | 0.80 |
Family history of colorectal cancer, n (%) | 0.65* | ||
Yes | 121 (37.5) | 71 (35.7) | |
No | 174 (53.9) | 106 (53.3) | |
Unknown | 28 (8.7) | 22 (11.1) | |
Tumor location, n (%) | 0.90* | ||
Right colon | 120 (37.2) | 78 (39.2) | |
Left colon | 80 (24.8) | 50 (25.1) | |
Rectum | 123 (38.1) | 71 (35.7) | |
Tumor histology, n (%) | 0.98**** | ||
Tubular adenocarcinoma | 295 (91.3) | 182 (91.4) | |
Poorly differentiated adenocarcinoma | 5 (1.5) | 2 (1.0) | |
Mucinous | 16 (5.0) | 12 (6.0) | |
Others | 7 (2.2) | 3 (1.5) | |
Pathological stage, n (%) | 0.83*** | ||
0 | 4 (1.2) | 6 (3.0) | |
I | 77 (23.8) | 50 (25.1) | |
II | 95 (29.4) | 53 (26.6) | |
III | 114 (35.3) | 71 (35.7) | |
IV | 33 (10.2) | 19 (9.5) | |
Frequency of dMMR, % | 8.0 | 13.1 | 0.09 |