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Fig. 5 | Hereditary Cancer in Clinical Practice

Fig. 5

From: Lynch-like syndrome with germline WRN mutation in Bulgarian patient with synchronous endometrial and ovarian cancer

Fig. 5

IHC analysis showing the loss of MLH1 (B) and PMS2 (C) nuclear protein expression (black stars) and preserved MSH2 (D) and MSH6 (E) nuclear expression (red stars), performed on the endometrial tumor tissue of the proband. Positive internal controls showed preserved nuclear expression in the stromal cells and lymphocytes (red arrow). IHC (Immunohistochemistry), magnification x400. For comparison – (A) - hematoxylin and eosin staining of the same slice, magnification x400

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Hereditary Cancer in Clinical Practice

ISSN: 1897-4287