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Table 1 Demographics of Respondents and Vaccination details

From: COVID-19 vaccination uptake and safety profile among germline BRCA1 and BRCA2 pathogenic variant carriers in Singapore

Completed COVID questionnaire (n = 189)

p-value

 

Personal history of cancer

(N = 130)

Nil history of cancer

(N = 59)

Gender

 Female

124 (95%)

38 (64%)

< 0.001+

 Male

6 (5%)

21 (36%)

Race

 Chinese

84 (65%)

44 (75%)

0.152*

 Malay

21 (16%)

7 (12%)

 Indian

13 (10%)

3 (5%)

 Others

12 (9%)

4 (7%)

 Unspecified

0

1 (2%)

Age, years

 Median (Range)

53.5 (28–79)

42.5 (22–77)

< 0.001#

 Mean (SD)

53.5 (±11.7)

45.7 (±14.0)

Germline pathogenic gene

 BRCA1

65 (50%)

32 (54%)

0.531+

 BRCA2

65 (50%)

27 (46%)

Types of cancer

 Breast

78 (60%)

NA

 

 Ovarian

28 (22%)

  

 Others

7 (5%)

  

 More than 1 cancer

16 (12%)

  

 Unspecified/No cancer

1 (1%)

  

COVID Vaccination

 Yes

116 (89%)

54 (92%)

0.796+

  1 dose

11 (8%)

1 (2%)

 

  2 doses

105 (81%)

51 (86%)

 

  Unspecified

0 (0%)

2 (3%)

 

 No

14 (11%)

5 (8%)

 

Previous COVID-19

 Yes

2 (2%)

0 (0%)

1.000*

 No

125 (96%)

59 (100%)

 

 Unspecified

3 (2%)

0 (0%)

 

Vaccinated individuals

 Type of Vaccination

N = 116

N = 54

0.806*

  Pfizer

97 (84%)

47 (87%)

 

  Moderna

13 (11%)

7 (13%)

 

  Sinovac

3 (3%)

0 (0%)

 

  Unspecified

3 (3%)

0 (0%)

 

Side effects post vaccination

 

 Yes

64 (55%)

28 (54%)

0.740+

  1 side effect

36 (31%)

15 (28%)

 

  2 side effects

20 (17%)

14 (26%)

 

  Multiple (> 2) side effects

8 (7%)

0 (%)

 

 No

50 (43%)

25 (46%)

 

  Unreported

2 (2%)

0 (%)

 
  1. *Based on Fisher’s exact test
  2. +Based on Pearson Chi-Square test
  3. #Based on t-test