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Table 4 Characteristics of studies included based on treatment regimens: carboplatin plus taxanes

From: Efficacy of different neoadjuvant treatment regimens in BRCA-mutated triple negative breast cancer: a systematic review and meta-analysis

 

Affiliation

Type of study

Stage of disease

Nº of BRCA1/2 mutated TNBC patients

pCR

Neoadjuvant treatment

Gonzalez-Rivera 2016 [39]

Spain

Observational

cohort

II-III

13

3

Cb-D

Echvarria 2018 [40]

Spain

non- randomized trial

I-III

9

5

Cb-D

Sharma 2017

PROGECT [41]

USA and Spain

Clinical trial

I-III

27

16

Cb-D

Sharma 2014 [9]

USA

Observational

II-III

14

12

Cb-D

Wunderlee 2018 [42]

Germany

Observational

cohort

I-III

15

11

Cb- P

Wang 2015 [43]

China

Observational

cohort

I-III

10

4

Cb-P

Menghi 2019 [44]

USA

Phase II Clinical Trial

II-III

9

8

Cb-P

Yuan 2020 [45]

USA

Phase II Clinical Trial

II-III

11

8

Cb-nab-P

  1. pCR Pathological complete response, Cb Carboplatin, D Docetaxel, P Paclitaxel, nab-P nab-paclitaxel