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Table 2 Characteristics of studies included based on treatment regimens: platin derivates (cisplatin or carboplatin) and anthracycline with/without taxanes

From: Efficacy of different neoadjuvant treatment regimens in BRCA-mutated triple negative breast cancer: a systematic review and meta-analysis

 

Affiliation

Type of study

Stage of disease

Nº of BRCA1/2 mutated TNBC patients

pCR

Neoadjuvant treatment

Saether 2018 [28]

Letonia

Retrospective

I-III

10

8

Cis—Dox

Holanek 2019 [29]

Czech Republic

Retrospective

I-III

37

21

Cis- A (18)

Cb-P-A (19)

Zhang 2021 [34]

China

Retrospective

I-III

18

9

Cb-A-T

Pohl-Rescigno 2020

GeparOcto [20]

Germany

RCT Phase III

I-III

35

26

Cb-Dox-P

Loib Ann 2018 [22]

15 countries

North America

Europe

Asia–Pacific

RCT Phase III

II-III

33

23

Cb-Dox-P

  1. pCR Pathological complete response, Cis Cisplatin, Cb Carboplatin, Dox Doxorubicin, P Paclitaxel, A Anthracycline based regimen, T taxane based regimen