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Table 11 Incidence of non-hematological adverse effects with different neoadjuvant treatment regimens

From: Efficacy of different neoadjuvant treatment regimens in BRCA-mutated triple negative breast cancer: a systematic review and meta-analysis

 

Cisplatin

alone

Carboplatin + anthracycline + taxane

Carboplatin + taxane

Carboplatin + Gemcitabine + PARPi

Carboplatin + NACT + PARPi

Carboplatin + NACT + anti VEGF antibody

PARPi

Carboplatin + Eribulin

n

196

106

239

93

398

1246

52

30

Adverse effect

 Gastrointestinal disorders

4.6%

2.8%

8.4%

24.7%

6.5%

27.7%

0.0%

0.0%

 Cardiac disorders

1.5%

0.0%

0.4%

1.1%

0.8%

6.7%

0.0%

0.0%

 Nervous system disorders

0,.0%

2.8%

1.3%

2.2%

0.8%

1.5%

0.0%

0.0%

 Renal and urinary disorders

1,.0%

0.0%

0.4%

1.1%

0.0%

4.8%

0.0%

3.3%

 Skin and subcutaneous tissue disorders

1.0%

0.0%

0.8%

0.0%

0.0%

7.1%

0.0%

0.0%