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Table 1 Participant characteristics (n = 21)

From: Attitudes toward preimplantation genetic testing and quality of life among individuals with hereditary diffuse gastric cancer syndrome

 

n (%)

Sociodemographics

Age, years (M ± SD)

51.4 ± 13.3; range: 30–75

Gender (Female)

17 (81.0)

Race (White/Caucasian)

19 (90.5)

Marital status

 Married or partnered

13 (61.9)

 Divorced or separated

5 (23.8)

 Single

3 (14.3)

Educational attainment

 Some college

4 (19.0)

 College graduate

6 (28.6)

 Post-graduate

11 (52.4)

Annual household incomea

  < $50,000

1 (4.8)

 $50,000-$100,000

9 (42.9)

 $100,000-$200,000

6 (28.6)

  > $200,000

4 (19.0)

Clinical history

Personal cancer history (Yes)

15 (71.4)

Personal cancer diagnosisb

 Lobular breast cancer

6 (28.6)

 Stomach cancer

13 (61.9)

 Other cancers

3 (4.8)

Number of 1st degree relatives with a HDGC cancer (M ± SD)

3 ± 2.8; range: 0–8

Number of 1st degree relatives who died from a HDGC cancer (M ± SD)

1 ± 2.4; range: 0–8

Total gastrectomya

 Yes, prophylactic

8 (38.1)

 Yes, prophylactic but occult gastric cancer detected

5 (23.8)

 Yes, due to gastric cancer

3 (14.3)

 No

4 (19.0)

Reproductive history

Have biological children (Yes)

15 (71.4)

Know biological children's CDH1 mutation statusc

 Yes, know all children’s statuses

6 (40.0)

 Yes, know some children’s statuses

5 (33.3)

 No

3 (20.0)

Have adopted children to eliminate the risk of a CDH1 mutation

0 (0)

Have used donor gametes (Yes)

0 (0)

Have used PGT and in vitro fertilization (Yes)

1 (4.8)

Want (more) biological children (Yes)a

2 (9.5)

  1. a Data were missing for one participant; percentages calculated out of total sample
  2. b Participants could endorse more than one cancer type
  3. c Percentages computed out of a total of 15 participants with biological children; 1 participant declined to respond