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Table 3 Decisional conflict, decision regret, anxiety, depression and distress

From: Mainstream genetic testing for women with ovarian cancer provides a solid basis for patients to make a well-informed decision about genetic testing

   

univariate

 

multivariate

 
 

Intervention group, n = 96

Control group, n = 91

mean diff or OR (95% CI)

p-value

mean diff or OR (95% CI)

p-value

Decisional conflict scale, mean (sd)

 - total score

19.7 (12.0)

19.3 (14.4)

0.4 (-3.5 – 4.3)

0.844

2.7 (-2.4 – 7.8)

0.294

 - uncertainty subscore

17.5 (19.8)

20.0 (21.3)

-2.5 (-8.6 – 3.5)

0.408

3.5 (-4.7 – 11.8)

0.402

 - informed subscore

20.2 (19.8)

19.1 (18.0)

1.1 (-3.7 – 5.9)

0.655

2.4 (-4.1 – 8.8)

0.472

 - support subscore

19.5 (13.9)

19.4 (16.9)

0.1 (-4.4 – 4.7)

0.947

0.4 (-5.8 – 6.7)

0.889

 - values clarity subscore

25.0 (16.2)

24.0 (17.4)

1.0 (-4.0 – 5.9)

0.702

2.9 (-3.8 – 9.6)

0.400

 - effective decision subscore

16.8 (15.7)

15.1 (14.8)

1.8 (-2.7 – 6.2)

0.433

3.8 (-2.3 – 10.0)

0.215

Decision regret scale, mean (sd)

      

 - total score

12.9 (13.2)

9.7 (11.0)

3.2 (-0.4 – 6.7)

0.079

4.9 (-0.7 – 9.7)

0.047*

HADS-Anxiety, mean (sd)

5.7 (4.1)

5.3 (3.7)

    

Subgroups, n (%)

 - ≤ 10

84 (87.5)

75 (82.4)

1.3 (0.6 – 3.1)

0.523

2.7 (0.8 – 9.2)

0.101

 - ≥ 11

11 (11.5)

13 (14.3)

 - missing

1 (1.0)

3 (3.3)

HADS-Depression, mean (sd)

4.6 (4.1)

3.6 (3.7)

    

Subgroups, n (%)

 - ≤ 10

84 (87.5)

86 (94.5)

0.5 (0.2 – 1.7)

0.291

0.7 (0.1 – 3.7)

0.715

 - ≥ 11

9 (9.4)

5 (5.5)

 - missing

3 (3.1)

0

Distress Thermometer, mean (sd)

3.9 (2.5)

3.7 (2.5)

    

Subgroups, n (%)

 - ≤ 3

46 (47.9)

49 (53.8)

0.8 (0.4 – 1.4)

0.418

0.6 (0.3 – 1.4)

0.270

 - ≥ 4

50 (52.1)

42 (46.2)

 - missing

0

0

  1. Decisional conflict and decision regret are measured on a scale of 0 to 100, with a higher score indicating more decisional conflict or regret
  2. For the continuous variables, i.e., decisional conflict scale and decision regret scale, the difference between the mean score for the control group and the intervention is shown (mean diff). For the dichotomous variables, i.e., HADS-Anxiety, HADS-Depression and Distress Thermometer, the odds ratio between the two groups is shown
  3. OR Odds Ratio, CI Confidence interval
  4. *p ≤ 0.05