Heterogeneity in the psychosocial and behavioral responses associated with a diagnosis of suspected Lynch syndrome in women with endometrial cancer

Table 1 Participant demographics (n = 15)

Criteria	Range / Categories (numbers)	Mean / Percentage
Age ^a	43–75 years	64 years
Age at EC diagnosis	41–72 years	60 years
Time since EC diagnosis	1–9 years	3.4 years
Time since genetic test result	0–2.4 years	1.3 years
States covered within Australia	Western Australia – 3	20%
	Queensland – 2	13.33%
	New South Wales – 2	13.33%
	Australian Capital Territory – 2	13.33%
	Victoria – 6	40%
Tumor MMR IHC results ^b	LOE MLH1/PMS2–9	60%
	LOE MSH2/MSH6–4	26.67%
	LOE MSH6–2	13.33%
Highest level of education	School level – 7	46.67%
	Bachelor’s Degree – 5	33.33%
	Master’s Degree – 3	20%
Occupation ^c	Nurse – 6	40%
	Other healthcare – 2	13.33%
	Other – 7	46.67%
Ethnicity	Caucasian – 13	86.67%
Ethnicity	Other – 2	13.33%
Stage of EC ^d	Stage 1–7	46.67%
	Stage 2–5	33.33%
	Stage 3–3	20%
Personal history of other cancers ^e	Breast cancer - 2	13.33%
Personal history of other cancers ^e	Bowel cancer - 1	6.67%
Family history of cancer ^f	≥1 first degree relative – 14	93.33%
Family history of cancer ^f	≥ 1 second or third degree relative – 13	86.67%

^a Age – at the time of study interview
^b LOE – Loss of Expression of gene in somatic tumor testing
^c Other occupations include accounts, insurance, journalism, government and education
^d FIGO staging in endometrial carcinomas [29]
^e Personal history of other primary cancers before the EC diagnosis
^f Family history of cancers included cancer of the uterus, bowel, brain, ureter, stomach, breast, ovary, lungs, throat, skin, prostate, liver, blood and pancreas
Abbreviations: EC Endometrial cancer, MMR Mismatch-repair, IHC Immunohistochemistry, LOE Loss of expression

ISSN: 1897-4287