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Table 5 Immunohistochemistry subtypes summary

From: Spectrum of germline pathogenic variants using a targeted next generation sequencing panel and genotype-phenotype correlations in patients with suspected hereditary breast cancer at an academic medical centre in Pakistan

Study Characteristics

N = number of tumors

% of total tumors

Breast Cancer (unilateral = 248, bilateral = 25)

298

100.00

Grade

 1

10

3.36

 2

123

41.28

 3

139

48.94

 Unknown

26

8.72

Histology

 IDC

257

86.24

 DCIS

22

7.38

 ILC

9

3.02

 Papillary

3

1.01

 Unknown

7

2.35

Immunohistochemistry

 Triple Negative (−)

71

23.83

 Triple Positive (+)

35

11.74

 ER−/PR+/HER2+

2

0.67

 ER−/PR+/HER2-

4

1.34

 ER−/PR-

3

1.01

 ER−/PR−/HER2+

24

8.05

 ER+/PR−/HER2-

13

4.36

 ER+/PR+/HER2-

115

38.59

 ER+/PR−/HER2+

5

1.68

 ER+/PR+

15

5.03

 ER+/PR-

1

0.34

 Unknown

10

3.36