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Table 4 Patient characteristics of the study participants

From: Spectrum of germline pathogenic variants using a targeted next generation sequencing panel and genotype-phenotype correlations in patients with suspected hereditary breast cancer at an academic medical centre in Pakistan

Study Characteristics Overview

N = number of patients

% of total patients

Total Study Participants

284

100.00

Males

5

1.76

Asymptomatic

1

0.35

Females

279

98.24

Asymptomatic

10

3.52

Unilateral

248

87.32

Bilateral

25

8.80

Asymptomatic

11

3.87

Breast and a secondary malignancy

5

1.76

Only breast

268

94.37

Asymptomatic

11

3.87

Family History of Disease

 Negative

75

26.41

 Positive 1st Degree Relative for Breast Cancer Related Malignancy

106

37.32

 Positive 2nd/3rd Degree Relative for Breast Cancer Related Malignancy

72

25.35

 Positive 1-3rd Degree Relative for Non-Breast Cancer Related Malignancy

27

9.51

 Incomplete Information

4

1.41