Variable | HBOC Odds Ratio (95% CI) | HBOC (female-only sample) Odds Ratio (95% CI) | Lynch Syndrome Odds Ratio (95% CI) | General Genetic Testinga Odds Ratio (95% CI) | Any Cancer Genetic Testingb Odds Ratio (95% CI) |
---|---|---|---|---|---|
Age | 1.24 (1.20, 1.28) | 1.25 (1.21, 1.29) | 1.22 (1.12, 1.36) | 1.04 (1.03, 1.06) | 1.06 (1.04, 1.07) |
Age (Squared) | 1.00 (1.00, 1.00) | 1.00 (1.00, 1.00) | 1.00 (1.00, 1.00) | 1.00 (1.00, 1.00) | 1.00 (1.00, 1.00) |
Modified Elixhauser Index | 1.08 (1.05, 1.12) | 1.07 (1.03, 1.10) | 1.12 (1.03, 1.20) | 1.13 (1.12, 1.14) | 1.13 (1.12, 1.14) |
Sex (reference = Male) Female | 18.91 (13.01, 28.86) | ------- | 1.93 (1.11, 3.51) | 0.90 (0.83, 0.99) | 1.22 (1.12, 1.32) |
Health Plan (reference = Commercial) | |||||
State employee | 1.65 (1.37, 1.97) | 1.64 (1.36, 1.97) | 1.66 (0.77, 3.34) | 4.54 (3.94, 5.23) | 2.66 (2.35, 3.00) |
Medicaid | 0.24 (0.18, 0.32) | 0.22 (0.17, 0.30) | 0.78 (0.36, 1.58) | 0.52 (0.43, 0.64) | 0.33 (0.28, 0.40) |
Medicare | 0.41 (0.30, 0.56) | 0.38 (0.27, 0.52) | 0.86 (0.41, 1.74) | 3.93 (3.45, 4.50) | 2.42 (2.16, 2.71) |
State Region (reference = Northwest) | 0.43 (0.31, 0.57) | 0.63 (0.26, 1.53) | 0.85 (0.72, 1.01) | 0.79 (0.68, 0.91) | |
West | 0.42 (0.31, 0.56) | ||||
East | 0.70 (0.57, 0.88) | 0.69 (0.56, 0.87) | 0.62 (0.28, 1.39) | 0.83 (0.71, 0.97) | 0.83 (0.72, 0.95) |
Central | 0.66 (0.52, 0.84) | 0.66 (0.52, 0.84) | 0.37 (0.13, 0.93) | 1.11 (0.95, 1.29) | 1.01 (0.88, 1.17) |
Northeast | 0.28 (0.15, 0.36) | 0.23 (0.14, 0.36) | 0.30 (0.06, 1.05) | 0.72 (0.58, 0.88) | 0.64 (0.53, 0.77) |
North Central | 0.59 (0.43, 0.80) | 0.56 (0.40, 0.77) | 1.47 (0.66, 3.38) | 0.51 (0.41, 0.63) | 0.54 (0.45, 0.65) |
Midwest | 0.42 (0.30, 0.57) | 0.41 (0.30, 0.57) | 0.69 (0.26, 1.76) | 1.20 (1.02, 1.42) | 1.07 (0.92, 1.27) |
Any Nicotine Usage (reference = No) | 0.88 (0.70, 1.11) | 0.90 (0.71, 1.13) | 1.05 (0.54, 1.95) | 1.07 (0.95, 1.20) | 1.01 (0.90, 1.12) |
Developmental Disorders (reference = No) | 0.85 (0.28, 1.92) | 0.97 (0.32, 2.20) | 0.43 (0.00, 3.09) | 1.11 (0.84, 1.44) | 1.12 (0.86, 1.44) |
Anxiety Disorders (referent = No) | 1.19 (0.99, 1.43) | 1.22 (1.01, 1.47) | 1.37 (0.75, 2.45) | 1.61 (1.45, 1.78) | 1.54 (1.40, 1.67) |
Other Mental Disorders (reference = No) | 1.53 (1.15, 2.00) | 1.56 (1.17, 2.05) | 4.36 (2.28, 7.98) | 1.60 (1.39, 1.83) | 1.59 (1.40, 1.80) |
Model c-statistic | 0.88 | 0.81 | 0.82 | 0.82 | 0.79 |
Model Brier score | <0.001 | <0.001 | <0.001 | 0.003 | 0.003 |