Reflex BRCA1 and BRCA2 tumour genetic testing for high-grade serous ovarian cancer: streamlined for clinicians but what do patients think?

Table 3 Univariable associations of continuous variables and MICRA scores

Variable	Distress		Uncertainty		Total Score
Variable	B (95% CI)	p-value	B (95% CI)	p-value	B (95% CI)	p-value
Age at diagnosis	−0.13 (− 0.29, 0.03)	0.11	− 0.35 (− 0.55, − 0.15)	< 0.001	− 0.43 (− 0.81, − 0.05)	0.03
Dispositional optimism	− 0.36 (− 0.66, − 0.04)	0.03	−0.66 (− 1.05, − 0.26)	0.001	− 1.23 (− 1.94, − 0.52)	< 0.001
Cancer-related distress
IES Intrusion	0.57 (0.41, 0.74)	< 0.001	0.79 (0.58, 1.00)	< 0.001	1.43 (1.05, 1.81)	< 0.001
IES Avoidance	0.18 (0.01, 0.37)	0.07	0.48 (0.25, 0.71)	< 0.001	0.59 (0.14, 1.04)	0.01
IES Total	0.25 (0.14, 0.35)	< 0.001	0.43 (0.32, 0.55)	< 0.001	0.68 (0.44, 0.92)	< 0.001
Knowledge	0.02 (− 0.14, 0.11)	0.78	−0.07 (− 0.23, 0.09)	0.40	− 0.06 (− 0.35, 0.23)	0.69

Univariable results from the subset of participants who completed the MICRA questionnaire (n = 63)

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