Table 2 Prevalence of BRCA1and BRCA2 mutations in ovarian cancer patients, by age of onset and family history.
From: Frequency of BRCA1 and BRCA2 mutations in ovarian cancer patients in South-East Poland
Number of cases | Number with a mutation | Proportion with a mutation (%) | |||||
|---|---|---|---|---|---|---|---|
BRCA1 | BRCA2 | BRCA1/2 together | BRCA1 | BRCA2 | BRCA1/2 together | ||
Age group | |||||||
≤ 50 | 31 | 3 | 1 | 4 | 9.7 | 3.2 | 12.9 |
> 50 | 127 | 8 | 6 | 14 | 6.3 | 4.7 | 11.0 |
Family history | |||||||
Positive | 39 | 6 | 4 | 10 | 15.4 | 10.2 | 26.6 |
Negative | 119 | 5 | 3 | 8 | 4.2 | 2.5 | 6.7 |
All cases together | 158 | 11 | 7 | 18 | 7.0 | 4.4 | 11.4 |