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Table 4 Clinical data of patients with pathogenic germline mutations and co-occurring mutations

From: Germline mutations among Polish patients with acute myeloid leukemia

Patient laboratory number Sex/age AML classification
(FAB)
Karyotype Family history of cancer Nucleotide change
IDH2 CEBPA GATA2 ETV6 TERT DDX41
10 M/44 M5 NK ND c.419G > A*
c.709 C > A
c.1018-19 C > T c.1770-24 C > T
c.3184G > A
c.936-23 C > G
c.1200 C > T
13 K/47 M1 NK CLL60 c.590_591insACCCGC* c.1075 C > A* c.936-23 C > G
c.1200 C > T
33 K/37 M6 NK ND c.337_344del* c.258G > A c.915G > A c.409 A > G
c.936-23 C > G
c.1200 C > T
43 M/20 M1 NK ND c.590_591insACCCGC* c.490G > A c.463 + 49G > A c.409 A > G
c.936-23 C > G
c.1200 C > T
47 M/51 M4 NK Pr72, Ut70 c.590_591insACCCGC* c.258G > A c.936-23 C > G
c.1200 C > T
83 K/49 M4 t(9;11) Br50 c.590_591insACCCGC* c.15 C > G
c.490G > A
c.936-23 C > G
97 M/48 M1 NK Bn62 c.419G > A* c.690G > T c.15 C > G c.936-23 C > G
  1. CLL - chronic lymphocytic leukemia, Pr - prostate cancer, Ut - uterine cancer, Br - breast cancer, Bn - brain cancer, FAB - French-American-British classification, (*) - germline mutation, NK - normal karyotype, ND - no data, (–) - no mutation