Table 2 Article list used to analyzed cancer penetrance associated to harmful lifestyle habit
Author/years | Reference | Study Design | Population | Sample Size | Control Group | Outcomes Measures | Main Conclusion |
|---|---|---|---|---|---|---|---|
Li H. 2020 | Cancer Epidemiol Biomarkers Prev | Cohort-study | BRCA1/2 mutation carriers | 13,118 | no | Alcohol consumption, smoking, | Smoking associated to BC risk for beginning to smoke more than 5 yers before full term pregnancy, no association with alcohol consumption |
Kehm RD. 2020 | Cancer Res | Cohort-study | BRCA1/2 mutation carriers | 15,550 | yes | Physical activity | Physical inactivity associated to 20% reduction BC risk |
Ko KP. 2018 | Int J Cancer | Longitudinal cohort study | BRCA1/2 mutation carriers | 7195 | no | Tobacco smoking | Tobacco smoking is associated with a modest increase of breast and ovarian cancer |
van Erkelens A. 2017 | J Genet Counsel | Cohort-Study | BRCA1/2 mutation carriers | 268,0 | no | Physical inactivity, smoking and alcohol consumption around childbearing age | Higher breast cancer risk in overweight women who drink alcohol, smoke and do not exercise |
Dennis J. 2010 | Breast | Case-control study | BRCA1/2 mutation carriers | 1925 | yes | Alcohol consumption | No association between alcohol consumption and BC risk |
Ginsburg O. 2009 | Breast Can Res Treat | Case-control study | BRCA1/2 mutation carriers | 2538 | yes | Smoking | Increase BC risk in BRCA 1 carriers with a past history of smoking |
Mc Guire V. 2006 | Cancer Epidemiol Biomarkers Prev | Case-control study | BRCA1/2 mutation carriers | 323,0 | yes | Alcohol consumption | No association between alcohol intake and BC risk |
Ghardirian P. 2004 | Int J Cancer | Case-control study | BRCA1/2 mutation carriers | 1097 | yes | Smoking | Smoking is not a risk factor for BC |