Fig. 1

Myxofibrosarcoma arising in the retroperitoneum of a 73-year-old man. A Representative magnetic resonance imaging findings of the tumor left abdominal wall. (Left) axial T1-, (middle) axial T2-, and (right) coronal T2-weighted images. B Gross images during surgery. (left) Preoperative skin incision design on the left abdominal wall. (right) After wide resection. Note that the 10th to 12th ribs, diaphragm, and peritoneum were resected in combination with the tumor. The spleen was preserved because the tumor had not invaded it grossly. C Hematoxylin eosin staining of the excised tumor. (left) Representative histology of the tumor, located mainly in the muscles and extended to the adipose tissues. (middle) Pleomorphic and spindled tumor region in a myxoid stroma. (right) Tumor region focally showing curvilinear vessels with a prominent myxoid matrix. D Family pedigree. Squares denote male family members, circles denote female family members, solid symbols show individuals affected by cancer, the arrow denotes the proband, a symbol with a slash indicates a deceased person (with the age at death), and the types of primary tumors are listed beside the symbols. P: proband, E: evaluation (MLH1 c.1233_1254dup22)