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Table 1 Participant demographics

From: Significant detection of new germline pathogenic variants in Australian Pancreatic Cancer Screening Program participants

Criteria

 

Number (%)

Gender

Male

107 (37.5)

 

Female

178 (62.5)

Ethnicity

White/Caucasian (non-Jewish)

249 (87.4)

 

White/Caucasian (Jewish)

19 (6.6)

 

Middle Eastern (non-Jewish)

4 (1.4)

 

Middle Eastern (Jewish)

1 (0.4)

 

Asian

2 (0.7)

 

Hispanic

2 (0.7)

 

Other/Unknown

8 (2.8)

  

Mean (Range)

Age

Overall

55.5 (27-79y)

 

Male

56.4 (30-78y)

 

Female

54.9 (27-79y)

PC Family History

Number of participants (Kindreds)

Youngest PC diagnosis in kindred (Years)

Mean (range)

FPC

203 (134)

58 (21–84)

BRCA2 GPV + ≥1FDR/SDR PC

55b (38)

59 (39–84)

PALB2 GPV + ≥1FDR/SDR PC

12c (7)

50 (25–76)

CDKN2A GPV + ≥1FDR/SDR PC

9 (4)

55 (43–71)

Lynch syndrome+ ≥ 1FDR/SDR PC

1 (1)

80

Hereditary Pancreatitis

2 (2)

54

Peutz-Jeghers syndromea

3 (3)

N/A

  1. aclinical diagnosis or STK11 GPV; b n = 2 at 50% risk; c n = 1 at 50% risk; GPV germline pathogenic variant; FDR first-degree relative; SDR second-degree relative