Deciding the operation type according to mismatch repair status among hereditary nonpolyposis colorectal cancer patients: should a tailored approach be applied, or does one size fit all?

Table 6 Univariate and multivariate analyses of clinicopathological features with OS and DFS among 181 HNPCC patients who underwent curative resection of CRC

Characteristics	n	OS (%)			p Value	Multiple Cox*
Characteristics	n	1 year	3 years	5 years	p Value	HR	95% CI	p Value
MMR with operation type
pMMR+EC	11	100	100	100	0.001	1
pMMR+SC	51	94.1	72.5	64.7		1.906	0.548–6.629	0.31
dMMR+EC	41	100	97.6	95.1		0.447	0.095–2.103	0.308
dMMR+SC	78	92.3	84.4	81.8		0.924	0.256–3.326	0.903
Characteristics	n	DFS (%)			p Value	Multiple Cox**
		1 year	3 years	5 years		HR	95% CI	p Value
MMR with operation type
pMMR+EC	11	100	100	100	0.002	1
pMMR+SC	51	94.1	72.5	64.7		1.814	0.530–6.207	0.343
dMMR+EC	41	97.6	95.1	90.2		0.467	0.108–2.026	0.309
dMMR+SC	78	88.4	77.9	75.3		1.476	0.434–5.017	0.532

ISSN: 1897-4287