Genetic testing reason | Meets reason pre-guideline n = 280 n (%) | Meets reason two-years post-guideline n = 301 n (%) | Meets reason four-years post-guideline n = 302 n (%) |
---|---|---|---|
Manchester score ≥ 16a* | 170/233 (73) | 152/242 (63) | 151/249 (61) |
BOADICEA score ≥ 10b | 6/7 (86) | 7/13 (54) | 10/23 (44) |
BRCAPRO score ≥ 10b | 33/48 (69) | 37/57 (65) | 27/52 (52) |
Individuals with triple negative breast cancer, (age ≤ 40 yrs)* | 72/280 (26) | 22/300 (7) | 24/301 (8) |
Individuals with isolated high-grade (Grades 2 & 3) invasive, non-mucinous ovarian, fallopian tube or primary peritoneal cancer (age ≤ 70 yrs)* | 11/280 (4) | 13/300 (4) | 20/302 (7) |
Individual with high-grade serous or endometroid (or invasive non-mucinous) ovarian, fallopian tube or primary peritoneal cancer and a family history* | 9/280 (3) | 19/301 (6) | 36/302 (12) |
Met at least one criterion | 192/243 (79) | 217/281 (77) | 220/281 (78) |