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Table 6 Clinical justification for GC recommendation according to GC referral status

From: Clinical implementation of an oncology‐specific family health history risk assessment tool

 

All with GC recommendation (n = 66)

GC referral(n = 24)

No GC referral (n = 42)

Personal medical history

BC diagnosis at age ≤ 50

41

18

23

Bilateral breast cancer

2

2

0

TNBC diagnosis age < 60

3

2

1

Ovarian cancer diagnosis

1

1

0

Endometrial cancer diagnosed at age < 50

1

0

1

Family history

≥ 1 relative with Li-Fraumeni syndrome related cancer + Personal BC diagnosis at age ≤ 45

9

1

8

≥ 1 relative with Li-Fraumeni syndrome related cancer at age ≤ 45

5

3

2

≥ 3 family members with same cancer

2

0

2

≥ 2 relatives with colorectal cancer

1

0

1

≥ 3 cases of Lynch syndrome related cancer in family

5

1

4

≥ 2 cases of breast, ovarian, pancreatic or prostate cancer in family

5

1

4

≥ 1 FDR with breast cancer at age ≤ 50

3

2

1

≥ 1 FDR with colorectal cancer at age < 50

3

2

1

≥ 1 FDR with ovarian cancer

2

0

2

Risk score

   

Manchester risk score meets criteria

13

6

7

  1. GC Genetic Counselling, TNBC Triple Negative Breast Cancer, FDR First Degree Relative