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Table 2 Participant characteristics and family health history parameters according to GC recommendation

From: Clinical implementation of an oncology‐specific family health history risk assessment tool

Characteristics

Completed

(n = 102)

GC recommendation

(n = 66)

No GC recommendation

(n = 36)

p-value

Mean age at enrollmenta (SD)

55.7 (9.0)

52.3 (7.8)

61.9 (7.7)

< 0.001

Mean age at BC diagnosisa (SD)

52.5 (9.2)

48.5 (7.5)

59.9 (7.2)

< 0.001

Mean years from BC diagnosis to enrollmenta (SD)

3.2 (3.7)

3.8 (4.2)

2.0 (2.1)

0.004

Mean Manchester scorea (SD)

4.1 (4.3)

5.7 (4.2)

1.2 (2.7)

< 0.001

Mean pedigree sizeb,c (SD)

10.7 (3.6)

10.7 (3.5)

10.7 (3.6)

0.986

Mean % relatives with unknown historyb (SD)

28.9 (19.5)

27.3 (17.7)

31.7 (22.4)

0.390

Mean % relatives with cancer historyb (SD)

15.2 (13.6)

16.9 (14.2)

12.0 (11.9)

0.093

Mean % relatives with age of cancer diagnosis reportedb,d (SD)

93.2 (16.7)

91.9 (17.5)

96.0 (14.6)

0.246

Racea

   

0.425

 Chinese

67 (65.7)

45 (68.2)

22 (61.1)

 

 Malay

17 (16.7)

8 (12.1)

9 (25.0)

 

 Indian

7 (6.9)

5 (7.6)

2 (5.6)

 

 Others

11 (10.8)

8 (12.1)

3 (8.3)

 

Breast Cancer stagea

  

0.760

 0

4 (3.9)

3 (4.5)

1 (2.8)

 

 I

20 (19.6)

15 (22.7)

5 (13.9)

 

 II

46 (45.1)

28 (42.4)

18 (50.0)

 

 III

12 (11.8)

7 (10.6)

5 (13.9)

 

 IV

17 (16.7)

12 (18.2)

5 (13.9)

 

Unknown

3 (2.9)

1 (1.5)

2 (5.6)

 

GC referral from clinical providera

  

< 0.001

 Yes

24 (23.5)

24 (36.4)

0

 

 No

78 (76.5)

42 (63.6)

36 (100.0)

 

Clinical providera

   

0.902

 Provider A

38 (37.3)

22 (33.3)

16 (44.4)

 

 Provider B

36 (35.3)

25 (37.9)

11 (30.6)

 

 Provider C

8 (7.8)

6 (9.1)

2 (5.6)

 

 Provider D

7 (6.9)

4 (6.1)

3 (8.3)

 

 Provider E

7 (6.9)

5 (7.6)

2 (5.6)

 

 Provider F

3 (2.9)

2 (3.0)

1 (2.8)

 

 Provider G

3 (2.9)

2 (3.0)

1 (2.8)

 
  1. GC Genetic Counselling, SD Standard Deviation, BC Breast cancer
  2. *(%) refers to the proportion of participants among those with GC referral
  3. ap-values were obtained from Pearson’s chi-square test for categorical variables and independent-
  4. samples t-test for continuous variables (p < 0.05)
  5. bp-values were obtained from Wilcoxon-rank sum test as FHH parameters not normally distributed (p < 0.05)
  6. c Excluding the participant
  7. d Restricted to families with at least one relative with cancer, excluding cancer types without age of diagnosis reported. If relative has more than 1 cancer type reported, age is reported for at least one of those