|
Patients with NLPHL
|
200
|
100
|
|
No data available
|
30
|
15
|
|
Malignancy related data available
|
170
|
65
|
|
Total families* of 170 patients
|
167
|
–
|
|
Male
|
130
|
76.5
|
|
Female
|
40
|
23.5
|
|
Median age
|
20.9 years
|
Range (5–64)
|
|
Age < 21
|
86
|
50.6
|
|
Type and frequency of familial malignancies
|
|
Family with no malignancy
|
77
|
46.1
|
|
Families with malignancy
|
90
|
53.9
|
|
Families with hematological only*
|
14
|
8.4
|
|
Families with hematological + solid
|
17
|
10.2
|
|
Families with solid cancers only
|
59
|
35.3
|
|
Total malignancies in family members
|
167
|
–
|
|
Total members with malignancy
|
162
|
–
|
|
Malignancy confirmed
|
73
|
43.7
|
|
Confirmed among 35 hematological**
|
28
|
80
|
|
Confirmed among 135 solid**
|
45
|
33.3
|
|
Malignancy unconfirmed
|
94
|
56.3
|
|
Unconfirmed among 35 hematological**
|
7
|
20
|
|
Unconfirmed among 135 solid**
|
90
|
66.66
|
|
First degree members
|
51
|
31.5
|
|
Second degree members
|
85
|
52.5
|
|
Third degree members
|
26
|
16
|
|
Common familial malignancy by groups*
|
|
Hematological malignancies
|
|
Non-Hodgkin lymphoma
|
16
|
9.6
|
|
Hodgkin lymphoma
|
11
|
6.6
|
|
Leukemia
|
8
|
4.8
|
|
Solid malignancies
|
|
Gastrointestinal
|
36
|
21.6
|
|
Female genital
|
13
|
7.8
|
|
Breast
|
18
|
10.77
|
|
Cancer not otherwise specified
|
19
|
11.4
|
|
Lung / Head and Neck
|
17
|
10.2
|
|
Others
|
27
|
16.17
|