Table 2 Prevalence of BRCA1 and BRCA2 mutations in ovarian cancer by age of onset and family history
From: BRCA1 and BRCA2 mutations in ovarian cancer patients from Belarus: update
Number of cases | Number with a mutation | Proportion with a mutation (%) | p-value | |
|---|---|---|---|---|
Age group | ||||
-50 | 54 | 19 | 35.2 | 0.0464 |
51+ | 160 | 35 | 21.9 | |
Family history | ||||
Positive for any cancer | 115 | 40 | 34.8 | |
Negative for any cancer | 96 | 14 | 14.6 | 0.0009 |
Positive for OC/BC | 55 | 28 | 50.9 | |
Negative for OC/BC | 156 | 26 | 16.7 | 0.0002 |
Unknown | 3 | – | 1,4 | |