Table 3 Questions regarding the experiences with recontacting for the additional CHEK2 mutation test
CHEK2 c.1100del PV | No CHEK2 c.1100del PV detected | Total | |||
|---|---|---|---|---|---|
N = 52 | N = 104 | ||||
Questions regarding recontacting | N | % | N | % | p-value |
Recontact appreciated | |||||
agree | 51 | 98.1% | 99 | 95.2% | n.s. |
neutral | 1 | 1.9% | 5 | 4.8% | |
disagree | 0 | 0.0% | 0 | 0.0% | |
Recontacting caused a lot of anxiety for myself | |||||
agree | 6 | 11.5% | 6 | 5.8% | n.s. |
neutral | 12 | 23.1% | 12 | 11.7% | |
disagree | 34 | 65.4% | 85 | 82.5% | |
Recontacting increased my worries for the family | |||||
agree | 8 | 15.4% | 2 | 1.9% | < 0.001 |
neutral | 17 | 32.7% | 4 | 3.9% | |
disagree | 27 | 51.9% | 97 | 94.2% | |
Written information sufficient for informed decision | |||||
agree | 50 | 96.2% | 99 | 96.1% | n.s. |
neutral | 1 | 1.9% | 3 | 2.9% | |
disagree | 1 | 1.9% | 1 | 1.0% | |
The decision for additional CHEK2 genetic testing was difficult | |||||
agree | 2 | 3.8% | 2 | 1.9% | n.s. |
neutral | 3 | 5.8% | 7 | 6.7% | |
disagree | 47 | 90.4% | 95 | 91.3% | |
Difficult to determine advantages and disadvantages of additional testing | |||||
agree | 5 | 9.6% | 8 | 7.7% | n.s. |
neutral | 7 | 13.5% | 20 | 19.2% | |
disagree | 40 | 76.9% | 76 | 73.1% | |
After receiving the CHEK2 test results | p-value | ||||
The results of the test were as expected | |||||
agree | 15 | 28.8% | 39 | 39.0% | 0.004 |
neutral | 19 | 36.5% | 49 | 49.0% | |
disagree | 18 | 34.6% | 12 | 12.0% | |
In retrospect I felt satisfied with having the choice for CHEK2 PV testing | |||||
agree | 51 | 98.1% | 97 | 96.0% | n.s. |
neutral | 1 | 1.9% | 4 | 4.0% | |
disagree | 0 | 0.0% | 0 | 0.0% | |
The test results influenced cancer worries counselee | |||||
no change in cancer worries | 35 | 67.3% | 89 | 88.1% | < 0.001 |
yes, increase of cancer worries | 14 | 26.9% | 1 | 1.0% | |
yes, decrease of cancer worries | 3 | 5.8% | 11 | 10.9% | |
The test results influenced cancer worries family members | |||||
no change in cancer worries | 22 | 42.3% | 81 | 80.2% | < 0.001 |
yes, increase of cancer worries | 27 | 51.9% | 0 | 0.0% | |
yes, decrease of cancer worries | 3 | 5.8% | 20 | 19.8% | |
Regrets about the choice for additional genetic testing | |||||
disagree | 52 | 100.0% | 103 | 99.0% | n.s. |
neutral | 0 | 0.0% | 1 | 1.0% | |
agree | 0 | 0.0% | 0 | 0.0% | |
Satisfaction with recontacting | |||||
good | 51 | 98.1% | 103 | 99.0% | n.s. |
fair | 1 | 1.9% | 1 | 1.0% | |
poor | 0 | 0.0% | 0 | 0.0% | |
Satisfaction with information prior to DNA-test | |||||
good | 46 | 88.5% | 97 | 97.1% | n.s. |
fair | 4 | 7.7% | 3 | 2.9% | |
poor | 2 | 3.8% | 0 | 0.0% | |
Satisfaction with information after test results | |||||
good | 49 | 94.2% | 97 | 93.3% | n.s. |
fair | 3 | 5.8% | 7 | 6.7% | |
poor | 0 | 0.0% | 0 | 0.0% | |