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Table 3 Questions regarding the experiences with recontacting for the additional CHEK2 mutation test

From: Recontacting non-BRCA1/2 breast cancer patients for germline CHEK2 c.1100del pathogenic variant testing: uptake and patient experiences

  CHEK2 c.1100del PV No CHEK2 c.1100del PV detected Total
N = 52 N = 104
Questions regarding recontacting N % N % p-value
Recontact appreciated
 agree 51 98.1% 99 95.2% n.s.
 neutral 1 1.9% 5 4.8%
 disagree 0 0.0% 0 0.0%
Recontacting caused a lot of anxiety for myself
 agree 6 11.5% 6 5.8% n.s.
 neutral 12 23.1% 12 11.7%
 disagree 34 65.4% 85 82.5%
Recontacting increased my worries for the family
 agree 8 15.4% 2 1.9% < 0.001
 neutral 17 32.7% 4 3.9%
 disagree 27 51.9% 97 94.2%
Written information sufficient for informed decision
 agree 50 96.2% 99 96.1% n.s.
 neutral 1 1.9% 3 2.9%
 disagree 1 1.9% 1 1.0%
The decision for additional CHEK2 genetic testing was difficult
 agree 2 3.8% 2 1.9% n.s.
 neutral 3 5.8% 7 6.7%
 disagree 47 90.4% 95 91.3%
Difficult to determine advantages and disadvantages of additional testing
 agree 5 9.6% 8 7.7% n.s.
 neutral 7 13.5% 20 19.2%
 disagree 40 76.9% 76 73.1%
After receiving the CHEK2 test results      p-value
The results of the test were as expected
 agree 15 28.8% 39 39.0% 0.004
 neutral 19 36.5% 49 49.0%
 disagree 18 34.6% 12 12.0%
In retrospect I felt satisfied with having the choice for CHEK2 PV testing
 agree 51 98.1% 97 96.0% n.s.
 neutral 1 1.9% 4 4.0%
 disagree 0 0.0% 0 0.0%
The test results influenced cancer worries counselee
 no change in cancer worries 35 67.3% 89 88.1% < 0.001
 yes, increase of cancer worries 14 26.9% 1 1.0%
 yes, decrease of cancer worries 3 5.8% 11 10.9%
The test results influenced cancer worries family members
 no change in cancer worries 22 42.3% 81 80.2% < 0.001
 yes, increase of cancer worries 27 51.9% 0 0.0%
 yes, decrease of cancer worries 3 5.8% 20 19.8%
Regrets about the choice for additional genetic testing
 disagree 52 100.0% 103 99.0% n.s.
 neutral 0 0.0% 1 1.0%
 agree 0 0.0% 0 0.0%
Satisfaction with recontacting
 good 51 98.1% 103 99.0% n.s.
 fair 1 1.9% 1 1.0%
 poor 0 0.0% 0 0.0%
Satisfaction with information prior to DNA-test
 good 46 88.5% 97 97.1% n.s.
 fair 4 7.7% 3 2.9%
 poor 2 3.8% 0 0.0%
Satisfaction with information after test results
 good 49 94.2% 97 93.3% n.s.
 fair 3 5.8% 7 6.7%
 poor 0 0.0% 0 0.0%