Diet, weight management, physical activity and Ovarian & Breast Cancer Risk in women with BRCA1/2 pathogenic Germline gene variants: systematic review

Coletta, Adriana M.; Peterson, Susan K.; Gatus, Leticia A.; Krause, Kate J.; Schembre, Susan M.; Gilchrist, Susan C.; Arun, Banu; You, Y. Nancy; Rodriguez-Bigas, Miguel A.; Strong, Larkin L.; Lu, Karen H.; Basen-Engquist, Karen

doi:10.1186/s13053-020-0137-1

Hereditary Cancer in Clinical Practice

Table 1 Risk of Bias Summary

From: Diet, weight management, physical activity and Ovarian & Breast Cancer Risk in women with BRCA1/2 pathogenic Germline gene variants: systematic review

Cancer Type	Author, Year	Selection Bias	Study Design	Confounders	Blinding	Data Collection Method	Withdrawals & Dropouts	Quality Score
Ovarian Cancer	Gronwald J et al., 2006	Strong	Moderate	Weak	N/A	Weak	N/A	Weak
	McGee J et al., 2012	Weak	Moderate	Strong	N/A	Moderate	N/A	Moderate
	Qian F et al., 2019	Strong	Moderate	Strong	N/A	Weak	N/A	Moderate
	Abbas S et al., 2019	Strong	Moderate	Weak	N/A	Strong	N/A	Moderate
Breast Cancer	Cybulski C et al., 2015	Strong	Moderate	Strong	N/A	Weak	N/A	Moderate
	Dennis J et al., 2010	Strong	Moderate	Strong	N/A	Moderate	N/A	Moderate
	Dennis J et al., 2011	Strong	Moderate	Strong	N/A	Strong	N/A	Strong
	Gronwald J et al., 2006	Strong	Moderate	Weak	N/A	Weak	N/A	Weak
	Kim SJ et al., 2019	Strong	Moderate	Strong	N/A	Moderate	N/A	Moderate
	King MC et al., 2003	Strong	Moderate	Moderate	N/A	Weak	N/A	Moderate
	Ko KP et al., 2013	Strong	Moderate	Strong	N/A	Strong	N/A	Strong
	Kotsopoulos J et al., 2005	Moderate	Moderate	Strong	N/A	Moderate	N/A	Moderate
	Lammert J et al., 2018	Strong	Moderate	Strong	N/A	Strong	N/A	Strong
	Lecarpentier J et al., 2011	Strong	Moderate	Strong	N/A	Moderate	N/A	Moderate
	Manders P et al., 2011	Strong	Moderate	Strong	N/A	Weak	N/A	Moderate
	McGuire V et al., 2006	Moderate	Moderate	Strong	N/A	Moderate	N/A	Moderate
	Moorman PG et al., 2010	Strong	Moderate	Weak	N/A	Moderate	N/A	Moderate
	Nkondjock A, Ghadirian P, et al., 2006	Strong	Moderate	Strong	N/A	Moderate	N/A	Moderate
	Nkondjock A, Robidoux A et al., 2006	Moderate	Moderate	Strong	N/A	Strong	N/A	Moderate
	Nkondjock A et al., 2007	Strong	Moderate	Strong	N/A	Strong	N/A	Strong
	Pijpe A et al., 2010	Moderate	Moderate	Strong	N/A	Moderate	N/A	Moderate
	Qian F et al., 2019	Strong	Moderate	Strong	N/A	Weak	N/A	Moderate

N/A = Not Applicable due to study design

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ISSN: 1897-4287

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