Measure | FAP group (n = 26) | Control group (n = 25) | p-value* | Simple LRM (coefficients) | p-value | Adjusted multivariate LRM** (coefficients) | p-value | Adjusted multivariate LRM*** (coefficients) | p-value | ||
---|---|---|---|---|---|---|---|---|---|---|---|
Mean | SD | Mean | SD | ||||||||
TONI-4 IQ | 90.5 | 5.6 | 95.6 | 6.8 | 0.005 | −5.1 | 0.005 | −5.2 | 0.005 | −5.0 | 0.008 |
BaterÃa III clusters | |||||||||||
 Verbal ability# | 88.2 | 7.7 | 95.7 | 7.8 | 0.001 | −7.5 | 0.001 | −7.4 | 0.001 | −7.2 | 0.002 |
 Thinking ability# | 80.5 | 10.5 | 97.8 | 10.3 | < 0.0001 | −17.3 | < 0.0001 | −16.7 | < 0.0001 | − 16.9 | < 0.0001 |
 Cognitive efficiency# | 81.1 | 11.9 | 94.7 | 9.9 | 0.0001 | −13.6 | < 0.0001 | − 13.4 | < 0.0001 | − 13.3 | < 0.0001 |
 Long-term memory# | 66.8 | 14.3 | 85.1 | 12.1 | < 0.0001 | −18.3 | < 0.0001 | −17.8 | < 0.0001 | − 18.3 | < 0.0001 |
 Processing speed# | 85.1 | 14.7 | 102.0 | 9.7 | < 0.0001 | −16.9 | < 0.0001 | − 16.6 | < 0.0001 | − 17.2 | < 0.0001 |
 Phonemic awareness | 88.6 | 10.8 | 97.6 | 8.7 | 0.002 | −8.9 | 0.002 | −8.7 | 0.002 | −8.5 | 0.004 |
 Working memory# | 84.4 | 10.7 | 95.6 | 11.4 | 0.0007 | − 11.1 | 0.001 | − 11.2 | 0.001 | −11.2 | 0.001 |
 Cognitive fluency# | 78.3 | 12.2 | 91.8 | 9.9 | 0.0001 | −13.5 | < 0.0001 | − 13.5 | < 0.0001 | − 14.8 | < 0.0001 |
 Executive processes# | 83.8 | 13.7 | 100.8 | 9.7 | < 0.0001 | −17.0 | < 0.0001 | − 17.0 | < 0.0001 | − 17.1 | < 0.0001 |
BRIEF-Adult | |||||||||||
 Inhibit | 49.3 | 7.9 | 47.1 | 7.0 | 0.319 | 2.3 | 0.319 | 2.4 | 0.305 | 2.0 | 0.385 |
 Shift | 51.8 | 10.3 | 48.9 | 11.9 | 0.256 | 2.9 | 0.391 | 3.2 | 0.391 | 2.9 | 0.396 |
 Emotional control | 51.5 | 8.6 | 47.7 | 10.2 | 0.067 | 3.9 | 0.180 | 4.0 | 0.162 | 3.6 | 0.225 |
 Self-monitor | 49.5 | 8.6 | 46.4 | 9.8 | 0.212 | 3.1 | 0.270 | 3.2 | 0.251 | 3.1 | 0.291 |
 Initiate | 50.5 | 10.9 | 49.2 | 9.4 | 0.795 | 1.3 | 0.677 | 1.5 | 0.626 | 1.5 | 0.642 |
 Working memory | 53.7 | 11.5 | 49.4 | 8.9 | 0.218 | 4.3 | 0.178 | 4.6 | 0.112 | 4.4 | 0.180 |
 Plan/Organize | 50.3 | 10.9 | 49.0 | 13.9 | 0.587 | 1.3 | 0.731 | 1.7 | 0.622 | 1.1 | 0.772 |
 Task monitor | 51.5 | 11.5 | 48.7 | 8.7 | 0.571 | 2.8 | 0.372 | 3.2 | 0.240 | 2.4 | 0.452 |
 Organization of materials | 49.8 | 8.2 | 50.3 | 8.7 | 0.870 | −0.4 | 0.870 | −0.2 | 0.929 | −0.7 | 0.779 |
 Behavior regulation index | 50.8 | 8.8 | 47.6 | 10.5 | 0.266 | 3.3 | 0.266 | 3.5 | 0.214 | 3.3 | 0.278 |
 Metacognitive index | 51.1 | 10.8 | 49.2 | 9.8 | 0.595 | 1.9 | 0.549 | 2.2 | 0.441 | 1.7 | 0.589 |
 Global executive composite | 51.1 | 10.0 | 48.3 | 10.1 | 0.272 | 2.8 | 0.356 | 3.1 | 0.264 | 2.7 | 0.389 |