Table 2 The Toronto and the SWEP53 protocol for adults
The Toronto protocol (2011) Adults | Breast cancer | Brain tumor | Soft tissue and bone sarcoma | Leukaemia or lymphoma | Colon cancer | Melanoma |
|---|---|---|---|---|---|---|
Monthly breast self-examination starting at age 18 years | Annual brain MRI | Annual rapid total body MRI | Blood test every 4 months: complete blood count, erythrocyte sedimentation rate, lactate dehydrogenase | Colonoscopy every 2 years, beginning at age 40 years, or 10 years before the earliest known colon cancer in the family | Annual dermatological examination | |
Clinical breast examination twice a year, starting at age 20–25 years, or 5–10 years before the earliest known breast cancer in the family | Ultrasound of abdomen and pelvis every 6 months | |||||
Annual mammography and breast MRI screening starting at age 20–25 years, or at earliest age of onset in the family | ||||||
Consider risk-reducing bilateral mastectomy | ||||||
The SWEP53 Protocol Adults | Breast cancer | Brain tumor | Soft tissue and bone sarcoma | Leukemia or lymphoma | Colon cancer | Melanoma |
Monthly breast self-examination starting at age 18 years | Annual brain MRI | Whole-body MRI | Only if there are known cases in the family | Only if there are known cases in the family. 10 years before the earliest known colon cancer in the family | Annual dermatological examination | |
Clinical breast examination once a year, starting at age 18 | ||||||
Annual breast MRI screening starting at age 18 and breast ultrasounds 6 month after the MRI | ||||||
Consider risk-reducing bilateral mastectomy |