Table 1 The Toronto and the SWEP53 protocol for children
The Toronto protocol (2011) children | Adrenocortical carcinoma | Brain tumor | Soft tissue and bone sarcoma | Leukaemia or lymphoma |
|---|---|---|---|---|
Ultrasound of abdomen and pelvis every 3–4 months | Annual brain MRI | Annual rapid total body MRI | Blood test every 4 months: complete blood count, erythrocyte sedimentation rate, lactate dehydrogenase | |
Complete urinalysis every 3–4 months | ||||
Blood tests every 4 months: β-human chorionic gonadotropin, alpha-fetoprotein, 17-OH-progesterone, testosterone, dehydroepiandrosterone sulfate, and rostenedione | ||||
The SWEP53 Protocol children | Ultrasound of abdomen and pelvis every 3–4 months Complete urinalysis every 3–4 months | None unless suspicion raised at the clinical check-up performed every 3 months | None unless suspicion raised at the clinical check-up performed every 3 months | None unless suspicion raised at the clinical check-up performed every 3 months |