Table 1 Patient, polyp and family history characteristics
From: Advanced adenomas may be a red flag for hereditary cancer syndromes
| N = 42 | |
|---|---|
| Mean age at polyp diagnosis, years | 44.6 (range 23–57) |
| Sex, n (%) | |
| Male | 19 (45.2) |
| Female | 23 (54.8) |
| Personal History of Synchronous/Metachronous AA | |
| Yes | 5 (11.9) |
| No | 37 (88.1) |
| FDR with CRC, n (%) | |
| Yes | 10 (23.8) |
| No | 32 (76.2) |
| Colonoscopy Indication | |
| Symptoms | 20 (47.6) |
| Screening for FH of CRC | 7 (16.7) |
| Average Risk Screening | 14 (33.3) |
| Polyp Surveillance | 1 (2.4) |
| Polyp Size, n (%) | |
| < 10 mm | 2 (4.8) |
| 10–20 mm | 21 (50.0) |
| 21–30 mm | 16 (38.1) |
| 31–40 mm | 2 (4.7) |
| > 40 mm | 1 (2.4) |
| Polyp Histology, n (%) | |
| Tubular adenoma | 39 (92.9) |
| Tubulovillous adenoma | 2 (4.8) |
| Villous adenoma | 1 (2.4) |
| Immunohistochemistry Results | |
| Not performed | 29 (69.0) |
| Normal | 12 (28.6) |
| Absence of MLH1/PMS2 | 1 (2.4) |
| Meets Amsterdam II Criteria, n (%) | |
| Yes | 3 (7.1) |
| No | 39 (92.9) |
| PREMM5 Score, n (%) | |
| ≥ 5 | 6 (14.3) |
| ≥ 2.5 | 14 (33.3) |
| Unable to calculate* | 15 (35.7) |