From: Advanced adenomas may be a red flag for hereditary cancer syndromes
N = 42 | |
---|---|
Mean age at polyp diagnosis, years | 44.6 (range 23–57) |
Sex, n (%) | |
Male | 19 (45.2) |
Female | 23 (54.8) |
Personal History of Synchronous/Metachronous AA | |
Yes | 5 (11.9) |
No | 37 (88.1) |
FDR with CRC, n (%) | |
Yes | 10 (23.8) |
No | 32 (76.2) |
Colonoscopy Indication | |
Symptoms | 20 (47.6) |
Screening for FH of CRC | 7 (16.7) |
Average Risk Screening | 14 (33.3) |
Polyp Surveillance | 1 (2.4) |
Polyp Size, n (%) | |
< 10 mm | 2 (4.8) |
10–20 mm | 21 (50.0) |
21–30 mm | 16 (38.1) |
31–40 mm | 2 (4.7) |
> 40 mm | 1 (2.4) |
Polyp Histology, n (%) | |
Tubular adenoma | 39 (92.9) |
Tubulovillous adenoma | 2 (4.8) |
Villous adenoma | 1 (2.4) |
Immunohistochemistry Results | |
Not performed | 29 (69.0) |
Normal | 12 (28.6) |
Absence of MLH1/PMS2 | 1 (2.4) |
Meets Amsterdam II Criteria, n (%) | |
Yes | 3 (7.1) |
No | 39 (92.9) |
PREMM5 Score, n (%) | |
≥ 5 | 6 (14.3) |
≥ 2.5 | 14 (33.3) |
Unable to calculate* | 15 (35.7) |