Table 1 Reported cases
From: Metaplastic carcinoma of the breast and BRCA1 germline mutation: a case report and review
Age | Family history | BRCA1 mutation | Subtype | Pathological type | |
|---|---|---|---|---|---|
Rashid et al [5]. | 22 | none | c.66_67 (E23fs) | TNBC | carcinosarcoma |
Noel et al [6]. | 49 | none | c.66dupA (E23fs) | TNBC | adenosquamous carcinoma |
Suspitsin et al [7]. | 35 | mother 52 years ovarian cancer | c.5266dupC (Q1756fs) | TNBC | carcinosarcoma |
Breuer et al [8]. | 25 | two paternal aunts 40 years or younger breast cancer | c.181 T>G (C61G) | TNBC | squamous cell carcinoma |
Hamad et al [9]. | 54 | none | (G511fs) | TNBC | osseous and chondroid metaplasia |
our case | 39 | mother 39 years breast cancer, maternal grandmother 61 years ovarian cancer | c. 188 T>A (L63*) | TNBC | chondroid metaplasia |