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Fig. 1 | Hereditary Cancer in Clinical Practice

Fig. 1

From: Metachronous cutaneous squamous cell carcinoma in a young patient as the only presenting symptom to uncover Lynch syndrome with MLH1 Germline mutation

Fig. 1

Histopathology of the cutaneous lesion showing a H&E × 40 of the groin lesion demonstrating proliferation of atypical keratinocytes in the dermis b groin lesions showing atypical keratinocytes containing abundance of cytoplasm with presence of keratin pearls (H&E × 100) c proliferation of atypical keratinocytes from a lesion in the antecubital fossa (H&E × 20) d High magnification of the arm lesion with cutaneous squamous cell carcinoma (H&E × 200) e skin lesion from the arm with PD-L1 expression < 1% of membranous tumor cell staining on immunohistochemical staining (DAKO PD-L1 28–8 clone)

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