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Table 4 Logit Models: Predicting Respondents Who Would Choose a Medicine for Susan

From: Preferences for breast cancer prevention among women with a BRCA1 or BRCA2 mutation

Characteristic

All Women

(N = 587), OR (95% CI)

Women Assigned to See Susan Age 25 Years and Medicine 1, a Denosumab-Like Medicine

(n = 285), OR (95% CI)

Women Assigned to See Susan Age 36 Years and Medicine 2, a Tamoxifen-Like Medicine

(n = 302), OR (95% CI)

Age 40 years or over

0.983 (0.568–1.703)

1.342 (0.636–2.831)

0.656 (0.274–1.571)

Hopes to have children in future (after mutation identified) or undecided

1.054 (0.604–1.838)

0.830 (0.378–1.823)

1.347 (0.580–3.129)

Time since genetic test

1.000 (0.957–1.046)

0.989 (0.929–1.052)

1.015 (0.948–1.086)

First-degree relative BC

1.354 (0.898–2.040)

1.072 (0.617–1.864)

1.924* (1.017–3.638)

First-degree relative OC

1.049 (0.659–1.669)

0.946 (0.496–1.807)

1.378 (0.680–2.795)

RRBM only

0.806 (0.441–1.473)

1.30 (0.545–3.392)

0.485 (0.209–1.127)

RRBSO only

1.325 (0.692–2.539)

1.915 (0.748–4.899)

1.010 (0.387–2.637)

RRBM and RRBSO

0.851 (0.456–1.586)

1.227 (0.503–2.993)

0.607 (0.235–1.570)

Higher education

0.880 (0.588–1.316)

1.325 (0.745–2.358)

0.584 (0.321–1.064)

Has taken a prescription medication, such as tamoxifen, raloxifene, or an aromatase inhibitor [anastrazole, exemestane]

1.799 (0.840–3.855)

0.850 (0.265–2.725)

3.321* (1.129–9.771)

Assigned to Susan, age 25 years

1.500* (1.031–2.183)

Not applicable

Not applicable

  1. BC Breast cancer, CI Confidence interval, OC Ovarian cancer, OR Odds ratio, RRBM Risk-reducing bilateral mastectomy, RRBSO Bilateral salpingo oophorectomy
  2. *Statistically significant at 95% confidence level