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Table 3 Logit Models: Predicting Respondents Who Would Choose a Medicine for Herself

From: Preferences for breast cancer prevention among women with a BRCA1 or BRCA2 mutation

Characteristic

All Women

(N = 598), OR (95% CI)

Women Assigned to See Medicine 1, a Denosumab-Like Medicine

(n = 289), OR (95% CI)

Women Assigned to See Medicine 2, a Tamoxifen-Like Medicine

(n = 309), OR (95% CI)

Age 40 years or over

0.953 (0.563–1.614)

1.446 (0.678–3.083)

0.651 (0.298–1.423)

Hopes to have children in future (after mutation identified) or undecided

0.792 (0.468–1.338)

0.772 (0.354–1.683)

0.806 (0.380–1.711)

Time since genetic test

1.051* (1.007–1.097)

1.095* (1.029–1.165)

1.014 (0.952–1.080)

First-degree relative with breast cancer

0.962 (0.657–1.409)

0.821 (0.474–1.422)

1.086 (0.627–1.879)

First-degree relative with ovarian cancer

1.240 (0.795–1.935)

1.401 (0.736–2.669)

1.305 (0.681–2.498)

RRBM only

0.693 (0.398–1.207)

1.284 (0.538–3.063)

0.468* (0.220–0.996)

RRBSO only

0.753 (0.408–1.390)

0.951 (0.385–2.349)

0.546 (0.224–1.331)

RRBM and RRBSO

0.383* (0.211–0.697)

0.331* (0.134–0.816)

0.424* (0.182–0.987)

Higher education

0.843 (0.573–1.241)

0.933 (0.524–1.663)

0.761 (0.440–1.316)

Has taken a prescription medication, such as tamoxifen, raloxifene, or an aromatase inhibitor [anastrazole, exemestane]

2.524* (1.198–5.316)

1.683 (0.565–5.015)

3.506* (1.214–10.124)

  1. CI Confidence interval, OR Odds ratio, RRBM Risk-reducing bilateral mastectomy, RRBSO Bilateral salpingo oophorectomy
  2. *Statistically significant at 95% confidence level