Public support for healthcare-mediated disclosure of hereditary cancer risk information: Results from a population-based survey in Sweden

Table 2 Respondents’ preferences on the disclosure of risk information in the scenario of moderate CRC risk

Group	Subgroup		*As relative:* Want to receive information about a potential hereditary CRC risk			Chi-square test^a	*As proband:* Want relatives to be informed about their potential hereditary CRC risk			Chi-square test^a
			Yes	No	NA	p-value	Yes	No	NA	p-value
Sex	Women	N	422	39	0		430	28	3
	Women	%	91.5	8.5	0		93.3	6.1	0.7
	Men	N	449	65	2		451	52	13
	Men	%	87.0	12.6	0.4		87.4	10.1	2.5
						0.04*				0.02*
Age	18–39	N	253	26	2		255	17	9
	18–39	%	90.0	9.3	0.7		90.7	6.0	3.2
	40–59	N	291	34	0		291	29	5
	40–59	%	89.5	10.5	0		89.5	8.9	1.5
	60–74	N	327	44	0		335	34	2
	60–74	%	88.1	11.9	0		90.3	9.2	0.5
						0.58				0.34
Education^b	Low	N	348	43	1		349	33	10
	Low	%	88.8	11	0.3		89.0	8.4	2.6
	Middle	N	278	34	1		280	28	5
	Middle	%	88.8	10.9	0.3		89.5	8.9	1.6
	High	N	240	26	0		246	19	1
	High	%	90.2	9.8	0		92.5	7.1	0.4
						0.87				0.69
Country of birth^c	Sweden	N	806	91	2		811	75	13
	Sweden	%	89.7	10.1	0.2		90.2	8.3	1.4
	Other	N	57	11	0		61	5	2
	Other	%	83.8	16.2	0		89.7	7.4	2.9
						0.18				0.98
Place of residence	City	N	674	81	1		686	59	11
	City	%	89.2	10.7	0.1		90.7	7.8	1.4
	Rural	N	194	22	1		192	21	4
	Rural	%	89.4	10.1	0.5		88.5	9.7	1.8
						0.92				0.45
Children^d	Yes	N	565	71	1		573	55	9
	Yes	%	88.7	11.1	0.2		90.0	8.6	1.4
	No	N	300	32	1		302	25	6
	No	%	90.1	9.6	0.3		90.7	7.5	1.8
						0.53				0.64
Single household^e	Yes	N	150	19	1		152	14	4
	Yes	%	88.2	11.2	0.6		89.4	8.2	2.4
	No	N	705	83	1		714	65	10
	No	%	89.4	10.5	0.1		90.5	8.2	1.3
						0.89				1.00
Personal cancer history^f	Yes	N	76	7	0		80	3	0
	Yes	%	91.6	8.4	0		96.4	3.6	0
	No	N	773	90	1		783	76	5
	No	%	89.5	10.4	0.1		90.6	8.8	0.6
						0.70				0.13
Total		N	871	104	2		881	80	16
Total		%	89.2	10.6	0.2		90.2	8.2	1.6

Shows respondents’ detailed characteristics versus reported preferences on the disclosure of risk information when answering as a proband, or an at-risk relative, belonging to a family with a moderately increased hereditary risk of CRC (10% lifetime risk)
^aChi-square tests compared proportions in the different groups
^bEducation levels clustered into Low (some elementary or high school education), Middle (post-secondary education < 3 years) or High (3 years of post-secondary education or more)
^cSelf-reported country of birth with response options; Sweden, Europe or Outside Europe
^dAs per response to the question; “Do you have children?”
^eHousehold status “single” corresponds to residing alone currently
^fHaving a current or past cancer diagnosis classified as yes, no previous or known cancer classified as no.

ISSN: 1897-4287