|
Genotype
|
Cases, n = 150 (%)
|
Controls, n = 150 (%)
|
ORa (95%CI)
|
p-value
|
|---|
|
MMP-1(rs1799750)
|
|
1G/1G
|
38 (25.3)
|
49 (32.7)
|
1
|
–
|
|
1G/2G
|
75 (50)
|
66 (44)
|
1.49 (0.87–2.55)
|
0.15
|
|
2G/2G
|
37 (24.7)
|
35 (23.3)
|
1.34 (0.70–2.56)
|
0.37
|
|
MMP-2(rs243865)
|
|
CC
|
88 (58.7)
|
88 (58.7)
|
1
|
–
|
|
CT
|
53 (35.3)
|
54 (36)
|
1.01 (0.59–1.67)
|
0.99
|
|
TT
|
9 (6)
|
8 (5.3)
|
1.27 (0.46–3.52)
|
0.65
|
|
MMP-7(rs11568818)
|
|
AA
|
52 (34.7)
|
53 (35.3)
|
1
|
–
|
|
AG
|
71 (47.3)
|
77 (51.3)
|
0.96 (0.56–1.65)
|
0.90
|
|
GG
|
27 (18)
|
20 (13.3)
|
1.41 (0.66–2.99)
|
0.38
|
|
MMP-13(rs2252070)
|
|
AA
|
79 (52.7)
|
70 (46.7)
|
1
|
–
|
|
AG
|
60 (40)
|
70 (46.7)
|
0.78 (0.50–1.24)
|
0.30
|
|
GG
|
11 (7.3)
|
10 (6.7)
|
0.95 (0.34–2.64)
|
0.92
|
|
MT2A(rs28366003)
|
|
AA
|
131 (87.3)
|
139 (92.7)
|
1
|
–
|
|
AG + GGb
|
19 (12.7)
|
11 (7.3)
|
1.76 (0.81–3.83)
|
0.15
|
- aMultivariable logistic regression adjusted for Zn level
- bGenotypes were summarized because of low number of GG genotype
