Table 3 Association of analyzed SNPs with lung cancer risk
Genotype | Cases, n = 199 (%) | Controls, n = 199(%) | ORa (95%CI) | p-value |
|---|---|---|---|---|
MMP-1(rs1799750) | ||||
1G/1G | 48 (24.1) | 47 (23.6) | 1 | – |
1G/2G | 114 (57.3) | 107 (53.8) | 0.98 (0.61–1.57) | 0.92 |
2G/2G | 37 (18.6) | 45 (22.6) | 0.77 (0.42–1.39) | 0.38 |
MMP-2(rs243865) | ||||
CC | 120 (60.3) | 121 (60.8) | 1 | – |
CT | 69 (34.7) | 72 (36.2) | 1.01 (0.65–1.55) | 0.98 |
TT | 10 (5) | 6 (3) | 1.64 (0.56–4.83) | 0.37 |
MMP-7(rs11568818) | ||||
AA | 70 (35.2) | 71 (35.7) | 1 | – |
AG | 98 (49.2) | 100 (50.3) | 1.03 (0.65–1.61) | 0.91 |
GG | 31 (15.6) | 28 (14.1) | 1.24 (0.63–2.44) | 0.54 |
MMP-13(rs2252070) | ||||
AA | 83 (41.7) | 96 (48.2) | 1 | – |
AG | 99 (49.7) | 87 (43.7) | 1.38 (0.89–2.14) | 0.15 |
GG | 17 (8.5) | 16 (8) | 1.26 (0.61–2.62) | 0.53 |
MT2A(rs28366003) | ||||
AA | 174 (87.4) | 180 (90.5) | 1 | – |
AG + GGb | 25 (12.6) | 19 (9.5) | 1.52 (0.72–3.18) | 0.27 |