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Table 4 Testing for BRCA Pathogenic Variants by Patient and Physician Characteristics

From: Adherence to National Comprehensive Cancer Network Guidelines for BRCA testing among high risk breast Cancer patients: a retrospective chart review study

 

N Patients

Patients tested, n (%)

Patients with any pathogenic varianta, n (%)

All patients

 Total patients included in the study

410

384 (93.7)

115 (29.9)

Race

 White

302

284 (94.0)

94 (33.1)

 Black or African American

69

63 (91.3)

15 (23.8)

 Asian

27

26 (96.3)

4 (15.4)

 Native Hawaiian

1

0 (0.0)

N/A

 Other

11

11 (100.0)

2 (18.2)

Cancer stage

 Metastatic breast cancer

124

114 (91.9)

42 (36.8)

 Early breast cancer

286

270 (94.4)

73 (27.0)

Clinical characteristics

 Metastatic and triple negative breast cancer

34

33 (97.1)

17 (51.5)

 Metastatic and HER2(−) breast cancer

105

98 (93.3)

39 (39.8)

 Triple negative breast cancer

126

121 (96.0)

50 (41.3)

Genetic counselor

 Yes

270

256 (94.8)

82 (32.0)

 No

140

128 (91.4)

33 (25.8)

  1. Abbreviations:BRCA Breast Cancer Gene, HER2 Human Epidermal Growth Factor Receptor 2
  2. aThe proportion was calculated out of number of patients tested within each category.