Fig. 1
From: A rare missense variant in APC interrupts splicing and causes AFAP in two Danish families
Pedigree of family 1 and 2, and segregation analyses of the APC variant c.289G>A, p.(Gly97Arg). Abbreviations: CRC: Colorectal cancer, adn: Colonic adenomas, DC: Duodenal cancer, LC: Hepatic cancer, MC: Breast cancer, EC: Endometrial cancer, PC: Pancreatic cancer, GC: Gastric cancer, n/a: Not available. Numbers in () refer to age at diagnosis (or death, if the person did not develop cancer). +: APC variant c.289G>A carrier, ?: APC variant c.289G>A carrier status unknown