Fig. 1

Pedigree structure of the Chinese family with hereditary ovarian syndrome. The affected family members are indicated with shading. Squares and circles denote males and females, respectively. Roman numerals indicate generations. The arrow indicates the proband (IV-7). A small red circle indicates which family members were tested for mutations and found to carry the mutation. A small hollow circle indicates which family members were tested and found not to carry the mutation. The numbers after cancer sites indicate the age at diagnosis. The age of death is reported if known. D, deceased