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Table 3 Subgroup analysis of registrants with neoplasms or advanced neoplasms

From: Outcomes of screening and surveillance in people with two parents affected by colorectal cancers: experiences from the Familial Bowel Cancer Service

Characteristic

No

All

 

No Advanced

Advanced

 

Neoplasms

Neoplasms

p-

Neoplasms

Neoplasms

 

(N = 56)

(N = 40)

value*

(N = 85)

(N = 11)

p-value*

Gender - Female

38 (67.8%)

18 (45.0%)

0.0251

51 (60.0%)

5 (45.5%)

0.3572

Screening/Surveillance

 Age at first screening (years)

43.4 ± 10.7

46.2 ± 10.6

0.2009

44.2 ± 10.8

47.5 ± 10.0

0.3329

 Duration of screening (years)

15.1 ± 10.4

20.3 ± 9.0

0.0107

16.9 ± 10.4

20.2 ± 7.8

0.2220

 Number of FOBTs

10.6 ± 9.3

12.8 ± 8.8

0.2393

11.2 ± 9.2

13.7 ± 7.1

0.3050

 Number of colonoscopies/sigmoidoscopies

3.4 ± 3.0

5.8 ± 2.7

0.0001

4.1 ± 3.0

6.5 ± 2.6

0.0125

Family History

 Age of Father at colorectal cancer diagnosis

65.8 ± 8.2

63.5 ± 9.6

0.2317

64.7 ± 9.0

66.2 ± 7.4

0.5529

 Age of Mother at colorectal cancer diagnosis

64.9 ± 10.7

64.2 ± 10.2

0.7478

64.3 ± 10.8

66.5 ± 7.2

0.4140

 At least one parent diagnosed at < 55

17 (30.4%)

9 (20.0%)

0.2543

24 (28.2%)

1 (9.1%)

0.1734

 At least one sibling with advanced neoplasm

5 (8.9%)

2 (5.0%)

0.4655

6 (7.1%)

1 (9.1%)

0.8073

 At least one sibling with neoplasm

16 (28.6%)

16 (40.0%)

0.2416

27 (31.8%)

5 (45.5%)

0.3648

  1. * p-value based on t-test for continuous variables and chi-square for binary variables, with p<0.05 considered statistically significant
  2. Plus-minus values are means ± SD