Table 4 Specific Mutations by Region
Region | Pathogenic Mutations | Polymorphisms | ||
|---|---|---|---|---|
BRCA1 | BRCA2 | BRCA1 | BRCA2 | |
Pacific | p.Thr790Ala p.Arg959Lys p.Glu1345Lys | p.Val859Ser*22 | p.Asp693Asn | p.Asp796Asn |
Caribbean | NO | NO | NO | p.Gln716Arg p.Asn991Asp c.1910-37dup |
Andean | NO | NO | NO | NO |
Coffee | NO | p.Leu771Phe p.Asn818Lys p.Lys1032Ile | NO | c.1909-33delA |
Eastern | NO | NO | NO | NO |