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Table 1 Breast Cancer Characteristics – all patients and by two age groups

From: Increased breast cancer risk in women with neurofibromatosis type 1: a meta-analysis and systematic review of the literature

 

All Patients

< 50

≥ 50

p

N

286

96

85

 

Age (year) a

 Mean + SEM

49.3 ± 13.1

39.3 ± 7.8

60.6 ± 7.6

 

 Range

4–81

4–49

49–81

 

Follow-up b (months)

 Mean ± SEM

44.7 ± 47.5

50.2 ± 53.3

34.5 ± 39.9

 

 Range

1.9–204

4–204

1.9–180

 

Breast Cancer Subtype

 Breast Carcinoma c

61.7%

36.5%

49.4%

0.192

 DCIS

1.7%

1.0%

2.4%

 IDC

28.9%

52.1%

35.3%

 ILC

3.1%

4.2%

5.9%

 Metaplastic

2.8%

3.1%

5.9%

 Sarcoma

1.1%

1.0%

1.2%

 Other

0.7%

2.1%

0%

Stage at Diagnosis

 Stage 0

1.9%

0%

3.7%

0.005

 Stage I

13.0%

14.8%

11.1%

 Stage II

46.3%

29.6%

63.0%

 Stage III

31.5%

51.9%

11.1%

 Stage IV

7.4%

3.7%

11.1%

Bilateral Breast Cancer

12.4%

16.1%

7.3%

0.229

Second Primary

27.3%

19.4%

37.5%

0.222

Developed Metastatic Disease

34.3%

38.5%

28.6%

0.445

Dead at last follow-up

46.7%

50%

41.7%

0.520

  1. a Age was not reported in 104 of cases; b Follow-up from breast cancer diagnosis; c Breast cancer subtype not specified